Evidence map›Paper›PMID 34858696›Full record

ArticleBiomedical optics express2021

Laser induced forward transfer isolating complex-shaped cell by beam shaping.

Peng Liang, Lindong Shang, Yuntong Wang, Martin J Booth, Bei Li

Abstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peng LiangState Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Changchun, 130033, China.ORCID https://orcid.org/0000-0002-3742-1461
Lindong ShangState Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Changchun, 130033, China.ORCID https://orcid.org/0000-0002-4689-2855
Yuntong WangState Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Changchun, 130033, China.ORCID https://orcid.org/0000-0002-4911-9446
Martin J BoothDepartment of Engineering Science, University of Oxford, Parks Road, Oxford, OX1 3PJ, United Kingdom.ORCID https://orcid.org/0000-0002-9525-8981
Bei LiState Key Laboratory of Applied Optics, Changchun Institute of Optics, Fine Mechanics and Physics, Changchun, 130033, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Beam shaping techniques have been widely used in holographic optical tweezers to accurately manipulate tiny particles and hologram optimization algorithms have also been widely reported to improve the optical trapping performance. In this paper, we presented a beam shaping laser induced forward transfer (BS-LIFT) technique to isolate complex-shaped cells. To do this, we built up a BS-LIFT instrument which combined beam shaping methods and laser induced forward transfer using liquid-crystal-on-silicon spatial light modulator. The laser beam was modulated into multiple desired points at the focal plane employing the Gerchberg-Saxton (GS) algorithm. Feasibility was verified through transferring various samples. To our knowledge, this is the first demonstration of BS-LIFT applied to the transfer complex-shaped cells. We successfully transferred cells whose size ranged from 1 µm to 100 µm. Our design will provide a novel approach for the application of this beam shaping technique and the isolation of single cells with variable shapes.

Identifiers

PMID34858696
PMCPMC8606160

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.