Evidence map›Paper›PMID 34858695›Full record

ArticleBiomedical optics express2021

Label-free imaging of age-related cardiac structural changes in non-human primates using multiphoton nonlinear microscopy.

Amara Khan, Fernanda Ramos-Gomes, Andrea Markus, Matthias Mietsch, Rabea Hinkel, Frauke Alves

Open access · goldAbstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Amara KhanMax-Planck-Institute for Experimental Medicine, Translational Molecular Imaging, Göttingen, Germany.ORCID https://orcid.org/0000-0002-6252-2061
Fernanda Ramos-GomesMax-Planck-Institute for Experimental Medicine, Translational Molecular Imaging, Göttingen, Germany.
Andrea MarkusMax-Planck-Institute for Experimental Medicine, Translational Molecular Imaging, Göttingen, Germany.
Matthias MietschDZHK (German Center for Cardiovascular Research), Partner site Göttingen, 37077 Göttingen, Germany.
Rabea HinkelDZHK (German Center for Cardiovascular Research), Partner site Göttingen, 37077 Göttingen, Germany.
Frauke AlvesMax-Planck-Institute for Experimental Medicine, Translational Molecular Imaging, Göttingen, Germany.
German Centre for Cardiovascular Research · DESociety of Interventional Radiology · USUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure is one of the most common causes of morbidity and mortality. Both maturational abnormalities and age-associated cardiac pathologies contribute to heart failure. Imaging-based assessment to discern detailed cardiac structure at various maturational stages is imperative for understanding mechanisms behind cardiac growth and aging. Using multiphoton nonlinear optical microscopy (NLOM) based label-free imaging, we investigated cardiac structural composition in a human-relevant aging model, the common marmoset monkey (

Identifiers

PMID34858695
PMCPMC8606147
OpenAlexW3200182270

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.