Evidence map›Paper›PMID 34858627›Full record

ArticleOxford medical case reports2021

Can lightning strike twice? Wild-type transthyretin cardiac amyloidosis associated with rare liver disease.

Priyanka T Bhattacharya, Alyson N Fox, Charles C Marboe, Stephen M Lagana, Helen E Remotti, Jeanine M D'Armiento, Monica P Goldklang, Andrew B Eisenberger, Jan M Griffin, Mathew S Maurer

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxford medical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Priyanka T BhattacharyaDepartment of Medicine, Columbia University Irving Medical Center, New York, NY, USA.ORCID https://orcid.org/0000-0001-6922-7084
Alyson N FoxDepartment of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Charles C MarboeDepartment of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
Stephen M LaganaDepartment of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
Helen E RemottiDepartment of Pathology & Cell Biology, Columbia University Irving Medical Center, New York, NY, USA.
Jeanine M D'ArmientoDepartment of Anesthesiology, Columbia University Irving Medical Center, New York, NY, USA.
Monica P GoldklangDepartment of Anesthesiology, Columbia University Irving Medical Center, New York, NY, USA.
Andrew B EisenbergerDepartment of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Jan M GriffinDepartment of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Mathew S MaurerDepartment of Medicine, Columbia University Irving Medical Center, New York, NY, USA.
Columbia University Irving Medical Center · US

Funding

SCAN-MP (Screening for Cardiac Amyloidosis with Nuclear imaging in Minority Populations) COVID-19 SuppplementR01HL139671 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAURER, MATHEW S, RUBERG, FREDERICK LIEF · 2019 to 2023
$7.4M
NHLBI NIH HHS R01 HL139671
6 · The paper itself

Abstract

Wild-type ATTR cardiac amyloidosis (ATTRwt-CA) is not as rare as previously thought to be. Patients with infiltrative cardiac amyloidosis often present with right-sided heart failure (HF) symptomatology. Clinically significant liver disease and cirrhosis has not been reported in ATTRwt-CA. We present two cases of ATTRwt-CA with right-sided HF and abnormal liver function tests initially thought to be secondary to congestive hepatopathy but found to have rare and unrelated liver disease. These cases highlight the importance of developing a broad differential diagnosis and leveraging a multidisciplinary team approach in evaluating patients for unusual causes of cirrhosis/other chronic liver diseases when ATTR cardiac amyloidosis patients present with congestive hepatopathy.

Identifiers

PMID34858627
PMCPMC8633595
OpenAlexW3217543189

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.