Evidence map›Paper›PMID 34858550›Full record

ArticleNutrition research and practice2021

Lomens-P0 (mixed extracts of

Yoon Seo Lee, Hyelin Jeon, Yang-Mi Her, Da Eun Lee, Yong Joon Jeong, Eun Jeong Kim, Tae Hwan Choe, Hee Ju Suh, Seung-Yeon Shin, Dae Won Park and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Nutrition research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Food science & nutrition · 2026
    Article
  2. A Mechanistic Study ofJournal of microbiology and biotechnology · 2025
    Article
  3. Nutrients · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Yoon Seo LeeDepartment of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0003-2927-0314
Hyelin JeonBioMedical Research Institute, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0001-9469-3677
Yang-Mi HerDepartment of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0001-6216-6565
Da Eun LeeDepartment of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0002-4985-1784
Yong Joon JeongResearch Institute, Genencell Co. Ltd., Yongin 16950, Korea.ORCID https://orcid.org/0000-0001-8823-0211
Eun Jeong KimResearch Institute, Genencell Co. Ltd., Yongin 16950, Korea.ORCID https://orcid.org/0000-0002-9448-0548
Tae Hwan ChoeDepartment of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0002-9975-5846
Hee Ju SuhDepartment of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0002-3162-6802
Seung-Yeon ShinDepartment of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0001-9104-6992
Dae Won ParkBioMedical Research Institute, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0003-4199-4446
Yeong-Geun LeeDepartment of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0002-9133-5783
Se Chan KangDepartment of Oriental Medicine Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Korea.ORCID https://orcid.org/0000-0003-0790-2237
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesPremenstrual syndrome (PMS) is a disorder characterized by repeated emotional, behavioral, and physical symptoms before menstruation, and the exact cause and mechanism are uncertain. Hyperprolactinemia interferes with the normal production of estrogen and progesterone, leading to PMS symptoms. Thus, we judged that the inhibition of prolactin hypersecretion could mitigate PMS symptoms. MATERIALS/

methods

resultsAnti-inflammatory effects of and prolactin secretion suppress by HVE and CZE were confirmed through

conclusionsThe Lomens-P0 suppressed the prolactin secretion in hyperprolactinemia mice, normalized the sex hormone imbalance, and significantly suppressed the expression of inflammatory markers in uterine tissue. This study suggests that Lomens-P0 may have the potential to prevent or remedy materials to PMS symptoms.

Indexed as

hormonesinflammationmedicinal plantsPremenstrual syndromeprolactin

Identifiers

PMID34858550
PMCPMC8601943
OpenAlexW3162388636

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.