Evidence map›Paper›PMID 34858522›Full record

ArticleAnalytical methods : advancing methods and applications2017

Characterization of bacteria causing acute otitis media using Raman microspectroscopy.

O D Ayala, C A Wakeman, I J Pence, C M O'Brien, J A Werkhaven, E P Skaar, A Mahadevan-Jansen

Open access · greenAbstract read
In one paragraph

Article in Analytical methods : advancing methods and applications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Label-Free Optical Technologies for Middle-Ear Diseases.Bioengineering (Basel, Switzerland) · 2024
    Review
  2. Review
  3. Article
  4. Differentiation of otitis media-causing bacteria and biofilmsFrontiers in cellular and infection microbiology · 2022
    Article
  5. Raman Spectroscopic Differentiation ofFrontiers in cellular and infection microbiology · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

O D AyalaDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
C A WakemanDepartment of Pathology, Microbiology, & Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
I J PenceDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
C M O'BrienDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
J A WerkhavenDepartment of Otolaryngology and Head and Neck Surgery, Vanderbilt University School of Medicine, Nashville, TN, USA.
E P SkaarDepartment of Pathology, Microbiology, & Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
A Mahadevan-JansenDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA.
Vanderbilt University · USCzech Academy of Sciences, Institute of Microbiology · CZTexas Tech University · US

Funding

The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
UT-Southwestern Clinical and Translational Alliance for Research (UT-STAR) (TL1)UL1TR000451 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2012 to 2012
$6.3M
A novel use of web-based software to efficiently triage pre-surgical patients basR44TR000045 · NCATS · MEDSLEUTH, INC. · PI KALAMAS, ALICIA GRUBER · 2012 to 2012
$546k
NCATS NIH HHS R44 TR000045NCATS NIH HHS UL1 TR000445NCATS NIH HHS UL1 TR000451
6 · The paper itself

Abstract

Otitis media (OM) is a prevalent disease that is the most frequent cause of physician visits and prescription of antibiotics for children. Current methods to diagnose OM and differentiate between the two main types of OM, acute otitis media (AOM) and otitis media with effusion (OME), rely on interpreting symptoms that may overlap between them. Since AOM requires antibiotic treatment and OME does not, there is a clinical need to distinguish between AOM and OME to determine whether antibiotic treatment is necessary and guide future prescriptions. We used an optical spectroscopy technique, Raman spectroscopy (RS), to identify and characterize the biochemical features of the three main pathogens that cause AOM

Indexed as

acute otitis mediabacteriacharacterizationidentificationRaman microspectroscopy

Identifiers

PMID34858522
PMCPMC8635270
OpenAlexW2589467990

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.