Evidence map›Paper›PMID 34858503›Full record

ArticleStem cells international2021

RAB37 Promotes Adipogenic Differentiation of hADSCs via the TIMP1/CD63/Integrin Signaling Pathway.

Haili Huang, Anran Li, Jin Li, Dan Sun, Ling Liang, Kunyan Pan, Chengzhang He, Peihua Zhang

Open access · goldAbstract read
In one paragraph

Article in Stem cells international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Haili HuangDepartment of Plastic Surgery, Affiliated Hospital of Guangdong Medical University, China.ORCID https://orcid.org/0000-0001-9099-7999
Anran LiDepartment of Plastic Surgery, Affiliated Hospital of Guangdong Medical University, China.ORCID https://orcid.org/0000-0002-7545-8214
Jin LiDepartment of Plastic Surgery, Affiliated Hospital of Guangdong Medical University, China.ORCID https://orcid.org/0000-0002-7670-3787
Dan SunDepartment of Plastic Surgery, Affiliated Hospital of Guangdong Medical University, China.ORCID https://orcid.org/0000-0002-2833-3806
Ling LiangDepartment of Plastic Surgery, Affiliated Hospital of Guangdong Medical University, China.ORCID https://orcid.org/0000-0003-2518-5067
Kunyan PanDepartment of Plastic Surgery, Affiliated Hospital of Guangdong Medical University, China.ORCID https://orcid.org/0000-0001-9632-2554
Chengzhang HeDepartment of Plastic Surgery, Affiliated Hospital of Guangdong Medical University, China.ORCID https://orcid.org/0000-0003-0494-4909
Peihua ZhangDepartment of Plastic Surgery, Affiliated Hospital of Guangdong Medical University, China.ORCID https://orcid.org/0000-0002-1567-0424
Guangdong Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The adipogenic differentiation ability of human adipose-derived mesenchymal stem cells (hADSCs) is critical for the construction of tissue engineering adipose, which shows promising applications in plastic surgery and regenerative medicine. RAB37 is a member of the small RabGTPase family and plays a critical role in vesicle trafficking. However, the role of RAB37 in adipogenic differentiation of hADSCs remains unclear. Here, we report that both the mRNA and protein levels of RAB37 fluctuated during adipogenic differentiation. Upregulation of RAB37 was observed at the early stage of adipogenic differentiation, which was accompanied by increased expression of transcription factors PPAR

Identifiers

PMID34858503
PMCPMC8632429
OpenAlexW3215571284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.