Evidence map›Paper›PMID 34858496›Full record

ArticleJournal of toxicology2021

Clothianidin and Thiacloprid Mixture Administration Induces Degenerative Damage in the Dentate Gyrus and Alteration in Short-Term Memory in Rats.

Alejandra Mora-Gutiérrez, Jorge Guevara, Carmen Rubio, Minerva Calvillo-Velasco, Daniela Silva-Adaya, Socorro Retana-Márquez, Blanca Espinosa, Carmen Martínez-Valenzuela, Moisés Rubio-Osornio

Open access · goldAbstract read
In one paragraph

Article in Journal of toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Alejandra Mora-GutiérrezDepartamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía, Ciudad de México 14269, Mexico.ORCID https://orcid.org/0000-0002-3988-4312
Jorge GuevaraDepartamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID https://orcid.org/0000-0003-3428-3179
Carmen RubioDepartamento de Neurofisiología, Instituto Nacional de Neurología y Neurocirugía, Ciudad de México 14269, Mexico.ORCID https://orcid.org/0000-0002-4775-5043
Minerva Calvillo-VelascoLaboratorio Experimental de Enfermedades Neurodegenerativas, Instituto Nacional de Neurología y Neurocirugía, 14269 Ciudad de México, Mexico.ORCID https://orcid.org/0000-0002-4652-1835
Daniela Silva-AdayaLaboratorio Experimental de Enfermedades Neurodegenerativas, Instituto Nacional de Neurología y Neurocirugía, 14269 Ciudad de México, Mexico.ORCID https://orcid.org/0000-0002-4679-5182
Socorro Retana-MárquezDepartamento de Biología de la Reproducción, Laboratorio R012, Universidad Autónoma Metropolitana, Unidad Iztapalapa, Ciudad de México 09340, Mexico.ORCID https://orcid.org/0000-0001-6360-8871
Blanca EspinosaDepartamento de Bioquímica, Instituto Nacional de Enfermedades Respiratorias, ICV, Ciudad de México 14080, Mexico.ORCID https://orcid.org/0000-0002-0215-8421
Carmen Martínez-ValenzuelaUnidad de Investigación en Ambiente y Salud, Universidad Autónoma de Occidente, Los Mochis, SIN, Mexico.ORCID https://orcid.org/0000-0003-1784-9986
Moisés Rubio-OsornioDepartamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía, Ciudad de México 14269, Mexico.ORCID https://orcid.org/0000-0001-9236-0609
Instituto Nacional de Neurología y Neurocirugía · MXInstituto Nacional de Enfermedades Respiratorias · MXUniversidad Autónoma de Occidente · MXUniversidad Autónoma Metropolitana · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonicotinoids are pesticides that act as agonists of nicotinic receptors for acetylcholine in insects' central nervous system (CNS). Chronic exposure to neonicotinoids in humans is related to autism, memory loss, and finger tremor. In this article, we evaluate the effect of subchronic oral administration of two neonicotinoids in the same mixture: clothianidin and thiacloprid. Decreasing doses of both pesticides were administered to rats starting from the lethal dose 50 (LD

Identifiers

PMID34858496
PMCPMC8632432
OpenAlexW3217247742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.