ArticleFrontiers in human neuroscience2021
Alteration of Whole Brain ALFF/fALFF and Degree Centrality in Adolescents With Depression and Suicidal Ideation After Electroconvulsive Therapy: A Resting-State fMRI Study.
Article in Frontiers in human neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Neurophysiological biomarkers of treatment response in suicidal ideation: a systematic review.Translational psychiatry · 2025Pooled it
- Interventions for suicidal and self-injurious related behaviors in adolescents with psychiatric disorders: a systematic review and meta-analysis.Translational psychiatry · 2025Pooled it
- Dynamic Changes in ALFF and DC in Subthreshold Depression Before and After ICBT Intervention.Neuropsychiatric disease and treatment · 2025Trial
- Alpha-band fronto-limbic hyperconnectivity in adolescents with major depression and suicidal ideation.BMC psychiatry · 2026Article
- Brain Functional Network Alterations in Adolescents With Major Depressive Disorder and Suicidal Attempt: A Resting-State fMRI Study.Alpha psychiatry · 2026Article
- Gender differences in gray matter volume of the anterior cingulate cortex and suicidal ideation in patients with major depressive disorder: evidence from the REST-meta-MDD project.Translational psychiatry · 2025Article
- Classify the fNIRS signals of first-episode drug-naive MDD patients with or without suicidal ideation using machine learning.BMC psychiatry · 2025Article
- Longitudinal analysis of brain functional connectivity and its association with clinical assessment in depressed patients using resting state fMRI.Scientific reports · 2025Article
- Structural brain changes in the anterior cingulate cortex of major depressive disorder individuals with suicidal ideation: Evidence from the REST-meta-MDD project.Psychological medicine · 2025Article
- Resting-state spontaneous brain activity as a neural marker for suicidal ideation in adolescents with non-suicidal self-injury: a voxel-wise and machine learning study.Frontiers in psychiatry · 2025Article
- Network analysis of depression, cognitive functions, and suicidal ideation in patients with diabetes: an epidemiological study in Iran.Acta diabetologica · 2024Article
- Lifetime Exposure to Depression and Neuroimaging Measures of Brain Structure and Function.JAMA network open · 2024Article
- Classification of female MDD patients with and without suicidal ideation using resting-state functional magnetic resonance imaging and machine learning.Frontiers in human neuroscience · 2024Article
- Towards dysfunctional connectome development in depressed adolescents.European child & adolescent psychiatry · 2023Article
- Sex differences of brain cortical structure in major depressive disorder.Psychoradiology · 2023Article
- Reduced suicidality after electroconvulsive therapy is linked to increased frontal brain activity in depressed patients: a resting-state fMRI study.Frontiers in psychiatry · 2023Article
- Aberrant degree centrality of functional brain networks in subclinical depression and major depressive disorder.Frontiers in psychiatry · 2023Article
- A retrospective case series of electroconvulsive therapy in the management of depression and suicidal symptoms in adolescents.Brain and behavior · 2022Article
- Identification of suicidality in patients with major depressive disorder via dynamic functional network connectivity signatures and machine learning.Translational psychiatry · 2022Article
- Risk factor analysis and nomogram construction for predicting suicidal ideation in patients with cancer.BMC psychiatry · 2022Article
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9 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
Major depressive disorder (MDD) is one of the most widespread mental disorders and can result in suicide. Suicidal ideation (SI) is strongly predictive of death by suicide, and electroconvulsive therapy (ECT) is effective for MDD, especially in patients with SI. In the present study, we aimed to determine differences in resting-state functional magnetic resonance imaging (rs-fMRI) in 14 adolescents aged 12-17 with MDD and SI at baseline and after ECT. All participants were administered the Hamilton Depression Scale (HAMD) and Beck Scale for Suicide Ideation (BSSI) and received rs-fMRI scans at baseline and after ECT. Following ECT, the amplitude of low frequency fluctuation (ALFF) and fractional ALFF (fALFF) significantly decreased in the right precentral gyrus, and the degree centrality (DC) decreased in the left triangular part of the inferior frontal gyrus and increased in the left hippocampus. There were significant negative correlations between the change of HAMD (ΔHAMD) and ALFF in the right precentral gyrus at baseline, and between the change of BSSI and the change of fALFF in the right precentral gyrus. The ΔHAMD was positively correlated with the DC value of the left hippocampus at baseline. We suggest that these brain regions may be indicators of response to ECT in adolescents with MDD and SI.
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