Evidence map›Paper›PMID 34858142›Full record

ArticleFrontiers in neural circuits2021

Midbrain Dopamine Neurons Defined by TrpV1 Modulate Psychomotor Behavior.

Gian Pietro Serra, Adriane Guillaumin, Sylvie Dumas, Bianca Vlcek, Åsa Wallén-Mackenzie

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neural circuits, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Increased sucrose consumption in mice gene-targeted forFrontiers in molecular neuroscience · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gian Pietro SerraUnit of Comparative Physiology, Department of Organism Biology, Uppsala University, Uppsala, Sweden.
Adriane GuillauminUnit of Comparative Physiology, Department of Organism Biology, Uppsala University, Uppsala, Sweden.
Sylvie DumasOramacell, Paris, France.
Bianca VlcekUnit of Comparative Physiology, Department of Organism Biology, Uppsala University, Uppsala, Sweden.
Åsa Wallén-MackenzieUnit of Comparative Physiology, Department of Organism Biology, Uppsala University, Uppsala, Sweden.
Uppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine (DA) neurons of the ventral tegmental area (VTA) continue to gain attention as far more heterogeneous than previously realized. Within the medial aspect of the VTA, the unexpected presence of TrpV1 mRNA has been identified. TrpV1 encodes the Transient Receptor Potential cation channel subfamily V member 1, TRPV1, also known as the capsaicin receptor, well recognized for its role in heat and pain processing by peripheral neurons. In contrast, the brain distribution of TrpV1 has been debated. Here, we hypothesized that the TrpV1

Indexed as

Dopaminergic NeuronsMesencephalonAnimalsGlutamic AcidMiceTRPV Cation ChannelsVentral Tegmental AreaVesicular Glutamate Transport Protein 2Glutamic AcidTRPV1 protein, mouseTRPV Cation ChannelsVesicular Glutamate Transport Protein 2amphetamineco-releaseglutamatepsychostimulantsensitizationtransient receptor vanilloidVGLUT2VMAT2

Identifiers

PMID34858142
PMCPMC8632262
OpenAlexW3214091110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.