Evidence map›Paper›PMID 34858004›Full record

ArticleAnnals of dermatology2021

Gender-Specific Differences in Gut Microbiota Composition Associated with Microbial Metabolites for Patients with Acne Vulgaris.

Yukun Huang, Lu Liu, Linna Chen, Lin Zhou, Xia Xiong, Yongqiong Deng

Open access · diamondAbstract read
In one paragraph

Article in Annals of dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
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  6. Article
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  8. Review
  9. Gut microbiota and psoriasis: pathogenesis, targeted therapy, and future directions.Frontiers in cellular and infection microbiology · 2024
    Review
  10. Frontiers in immunology · 2023
    Article
  11. Review
  12. Review
  13. Review
  14. Truncal Acne: An Overview.Journal of clinical medicine · 2022
    Review
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yukun HuangDepartment of Dermatology, Affiliated Hospital of Southwest Medical University, Luzhou, China.ORCID https://orcid.org/0000-0002-0364-486X
Lu LiuDepartment of Dermatology, Affiliated Hospital of Southwest Medical University, Luzhou, China.ORCID https://orcid.org/0000-0002-3033-0655
Linna ChenDepartment of Dermatology, Affiliated Hospital of Southwest Medical University, Luzhou, China.ORCID https://orcid.org/0000-0003-4383-9319
Lin ZhouDepartment of Dermatology, Affiliated Hospital of Southwest Medical University, Luzhou, China.ORCID https://orcid.org/0000-0002-0445-0354
Xia XiongDepartment of Dermatology, Affiliated Hospital of Southwest Medical University, Luzhou, China.ORCID https://orcid.org/0000-0002-8282-1309
Yongqiong DengDepartment of Dermatology, Affiliated Hospital of Southwest Medical University, Luzhou, China.ORCID https://orcid.org/0000-0003-2023-830X
Affiliated Hospital of Southwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe gut microbial dysbiosis and gender differences in the pathogenesis of acne vulgaris have long been postulated respectively. However, there was no data about a gender-related discrepancy in gut microbiota and microbial metabolism in acne.

objectiveThis study aimed at identifying the underlying gender-related difference in gut microbiota and metabolism in acne vulgaris.

methodsFecal samples were collected from 43 acne patients and 43 age and gender-matched controls. Gut microbiota was analyzed by sequencing the V3-V4 region of

resultsCompared with healthy controls, the men had a lower abundance of 18 microbes such as

conclusionThe disorder of gut microbiota and metabolism in acne vulgaris was gender-specific, which supported the potential role of gender difference in the pathogenesis of this disease.

Indexed as

Acne vulgarisGastrointestinal microbiomeGender differencesMetabolites

Identifiers

PMID34858004
PMCPMC8577912
OpenAlexW3212809431

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.