Evidence map›Paper›PMID 34858001›Full record

ArticleAnnals of dermatology2021

Consensus Update for Systemic Treatment of Atopic Dermatitis.

Ji Hyun Lee, Jung Eun Kim, Gyeong-Hun Park, Jung Min Bae, Ji Yeon Byun, Min Kyung Shin, Tae Young Han, Seung Phil Hong, Yong Hyun Jang, Hye One Kim and 10 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 15 institutions in 2 countries.

Ji Hyun LeeDepartment of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0002-3671-502X
Jung Eun KimDepartment of Dermatology, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0003-1670-0995
Gyeong-Hun ParkDepartment of Dermatology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.ORCID https://orcid.org/0000-0001-8890-8678
Jung Min BaeDepartment of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID https://orcid.org/0000-0001-5975-8519
Ji Yeon ByunDepartment of Dermatology, Ewha Womans University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4519-9474
Min Kyung ShinDepartment of Dermatology, Kyung Hee University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9834-7931
Tae Young HanDepartment of Dermatology, Nowon Eulji Medical Center, Eulji University, Seoul, Korea.ORCID https://orcid.org/0000-0003-0317-9635
Seung Phil HongDepartment of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-0684-498X
Yong Hyun JangDepartment of Dermatology, School of Medicine, Kyungpook National University, Kyungpook National University Hospital, Daegu, Korea.ORCID https://orcid.org/0000-0003-1706-007X
Hye One KimDepartment of Dermatology, Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.ORCID https://orcid.org/0000-0001-5846-0008
Chan Ho NaDepartment of Dermatology, College of Medicine, Chosun University, Gwangju, Korea.ORCID https://orcid.org/0000-0001-5259-5382
Bark-Lynn LewDepartment of Dermatology, Kyung Hee University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4443-4161
JiYoung AhnDepartment of Dermatology, National Medical Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-6766-9978
Chang Ook ParkDepartment of Dermatology, Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3856-1201
Young-Joon SeoDepartment of Dermatology, Chungnam National University College of Medicine, Daejeon, Korea.ORCID https://orcid.org/0000-0002-4955-590X
Yang Won LeeDepartment of Dermatology, Konkuk University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-1268-1248
Sang Wook SonDepartment of Dermatology, Korea University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3332-7056
Eung Ho ChoiDepartment of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea.ORCID https://orcid.org/0000-0002-0148-5594
Young Lip ParkDepartment of Dermatology, Soonchunhyang University Bucheon Hospital, Bucheon, Korea.ORCID https://orcid.org/0000-0002-6532-3156
Joo Young RohDepartment of Dermatology, Gil Medical Center, Gachon University School of Medicine, Incheon, Korea.ORCID https://orcid.org/0000-0002-9878-6691
Yonsei University · KRKyung Hee University · KRSacred Heart Hospital · NGThe Catholic University of Korea Seoul St. Mary's Hospital · KRChosun University · KRChungnam National University · KREulji University · KREwha Womans University · KRGachon University Gil Medical Center · KRKonkuk University · KRKorea University · KRKyungpook National University Hospital · KRNational Medical Center · KRSoonchunhyang University · KRThe Catholic University of Korea St. Vincent's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2015, the Korean Atopic Dermatitis Association (KADA) working group published consensus guidelines for treating atopic dermatitis (AD).

objectiveWe aimed to provide updated consensus recommendations for systemic treatment of AD in South Korea based on recent evidence and experience.

methodsWe compiled a database of references from relevant systematic reviews and guidelines on the systemic management of AD. Evidence for each statement was graded and classified based on thestrength of the recommendation. Forty-two council members from the KADA participated in three rounds of voting to establish a consensus on expert recommendations.

resultsWe do not recommend long-term treatment with systemic steroids forpatients with moderate-to-severe AD due to the risk of adverse effects. We recommend treatment with cyclosporine or dupilumab and selective treatment with methotrexate or azathioprine for patients with moderate-to-severe AD. We suggest treatment with antihistamines as an option for alleviating clinical symptoms of AD. We recommend selective treatment with narrowband ultraviolet B for patients with chronic moderate-to-severe AD. We do not recommend treatment with oral antibiotics for patients with moderate-to-severe AD but who have no signs of infection. We did not reach a consensus on recommendations for treatment with allergen-specific immunotherapy, probiotics, evening primrose oil, orvitamin D for patients with moderate-to-severe AD. We also recommend educational interventions and counselling for patients with AD and caregivers to improve the treatment success rate.

conclusionWe look forward to implementing a new and updated consensus of systemic therapy in controlling patients with moderate-to-severe AD.

Indexed as

Atopic dermatitisConsensusRepublic of KoreaSystemic treatmentTherapeutics

Identifiers

PMID34858001
PMCPMC8577915
OpenAlexW3211487863

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.