Evidence map›Paper›PMID 34857820›Full record

ArticleScientific reports2021

The optics of the human eye at 8.6 µm resolution.

Sergio Bonaque-González, Juan M Trujillo-Sevilla, Miriam Velasco-Ocaña, Óscar Casanova-González, Miguel Sicilia-Cabrera, Alex Roqué-Velasco, Sabato Ceruso, Ricardo Oliva-García, Javier Martín-Hernández, Oscar Gomez-Cardenes and 4 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 3 countries.

Sergio Bonaque-GonzálezWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain. sergiob@wooptix.com.
Juan M Trujillo-SevillaWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain.
Miriam Velasco-OcañaWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain.
Óscar Casanova-GonzálezWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain.
Miguel Sicilia-CabreraWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain.
Alex Roqué-VelascoWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain.
Sabato CerusoWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain.
Ricardo Oliva-GarcíaWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain.
Javier Martín-HernándezWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain.
Oscar Gomez-CardenesWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain.
José G Marichal-HernándezWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain.
Damien GatinelRothschild Foundation Hospital, 29 Rue Manin, Paris, France.
Jack T HolladayBaylor College of Medicine, Houston, TX, USA.
José M Rodríguez-RamosWooptix S.L. Avda, Trinidad 61 Planta 7, La Laguna, Tenerife, Canary Islands, Spain. jmramos@wooptix.com.
TiGenix (Spain) · ESBaylor College of Medicine · USFondation de Rothschild · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ocular optics is normally estimated based on up to 2,600 measurement points within the pupil of the eye, which implies a lateral resolution of approximately 175 µm for a 9 mm pupil diameter. This is because information below this resolution is not thought to be relevant or even possible to obtain with current measurement systems. In this work, we characterize the in vivo ocular optics of the human eye with a lateral resolution of 8.6 µm, which implies roughly 1 million measurement points for a pupil diameter of 9 mm. The results suggest that the normal human eye presents a series of hitherto unknown optical patterns with amplitudes between 200 and 300 nm and is made up of a series of in-phase peaks and valleys. If the results are analysed at only high lateral frequencies, the human eye is also found to contain a whole range of new information. This discovery could have a great impact on the way we understand some fundamental mechanisms of human vision and could be of outstanding utility in certain fields of ophthalmology.

Indexed as

HumansOptics and PhotonicsPupilVision, Ocular

Identifiers

PMID34857820
PMCPMC8640020
OpenAlexW3217164280

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.