ArticleScientific reports2021
A large-scale population-based epidemiological study on the prevalence of central sensitization syndromes in Japan.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Central sensitization in women with endometriosis: a cross-sectional study.BMC women's health · 2026Observational
- Article
- Central Sensitization-Related Symptoms and Influencing Factors on Health-Related Quality of Life among Frail Older Adults in Senior Day Care Centers: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2024Article
- Article
- Sex differences in conditioned pain modulation effects and its associations with autonomic nervous system activities in healthy, younger individuals: a pilot study.Pain reports · 2024Article
- Blink rate during saccadic eye movements: insights from patients with chronic pain.Journal of medicine and life · 2024Article
- Characterizing clinical progression in patients with musculoskeletal pain by pain severity and central sensitization-related symptoms.Scientific reports · 2024Article
- The Influence of Physical, Mental, and Cognitive Factors on Health-Related Quality of Life among Community-Dwelling Older Adults: A Focus on Central Sensitization-Related Symptoms.Geriatrics (Basel, Switzerland) · 2024Article
- Central sensitization negatively influences the level of disability in female patients with anterior knee pain.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Central Sensitization in Cancer Survivors and Its Clinical Implications: State of the Art.Journal of clinical medicine · 2023Review
- Cultural Validation of the Chinese Central Sensitization Inventory in Patients with Chronic Pain and its Predictive Ability of Comorbid Central Sensitivity Syndromes.Journal of pain research · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A cross-sectional study of 21,665 Japanese residents was performed to investigate the prevalence of central sensitization syndromes (CSS). CSS were assessed using the Central Sensitization Inventory (CSI-A). CSS were defined as a CSI-A score of 40 or higher. Age, sex, district, 10 CSS-related diseases (CSI-B), lifestyle, and mental factors were rated in a self-reported survey. The prevalence of CSS and its relationship with potential factors were examined by sex using descriptive and logistic regression models. The prevalence of CSS was 4.2% in all participants and was significantly higher in women (4.9%) than in men (2.7%). Adjusted odds ratios correlated with CSS for an age of 80-97 years versus 60-79 years (2.07 and 2.89), one or more CSI-B diseases (3.58 and 3.51), few sleeping hours (2.18 and 1.98), high perceived stress (5.00 and 4.91), low (2.94 and 2.71) and high (0.45 and 0.66) resilience versus moderate resilience, and exercise habits (0.68 and 0.55) in men and women (all P < 0.05). The relationship between CSS and age 20 and 59 years, ex-smokers, coffee intake, and alcohol intake differed by sex. The prevalence of CSS was estimated to be low in the healthy population. CSS correlated with CSS-related diseases and some positive and negative factors.
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