Evidence map›Paper›PMID 34857785›Full record

ArticleScientific reports2021

Routine COVID-19 testing may not be necessary for most cancer patients.

Ali Motlagh, Fatemeh Elmi, Maisa Yamrali, Mansour Ranjbar, Mehrdad Azmin, Farzaneh Moshiri, Christoph Hamelmann, Slim Slama, Nadia Tavakoli, Asmus Hammerich and 8 more

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Association of Cancer History with COVID-19 Risk and Outcomes among Older Postmenopausal Women: Results from the Women's Health Initiative.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2025
    Article
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ali MotlaghDepartment of Radiation Oncology, Imam Hossein Hospital, Shaheed Beheshti Medical University, Tehran, Iran.
Fatemeh ElmiDepartment of Radiation Oncology, Imam Hossein Hospital, Shaheed Beheshti Medical University, Tehran, Iran.
Maisa YamraliNational Cancer Control Secretariat, Ministry of Health and Medical Education, Tehran, Iran. maisa.yamralii@gmail.com.ORCID 0000-0002-6009-1157
Mansour RanjbarWHO Country Office, Tehran, Iran.
Mehrdad AzminNon-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Farzaneh MoshiriDepartment of Biotechnology, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
Christoph HamelmannWHO Country Office, Tehran, Iran.
Slim SlamaWHO Regional Office for Eastern Mediterranean Region, Cairo, Egypt.
Nadia TavakoliDepartment of Cell and Molecular Sciences, Faculty of Biological Sciences, Kharazmi University, Tehran, Iran.
Asmus HammerichWHO Regional Office for Eastern Mediterranean Region, Cairo, Egypt.
Nasim PourghazianWHO Regional Office for Eastern Mediterranean Region, Cairo, Egypt.
Marzeyeh Soleymani NejadWHO Country Office, Tehran, Iran.
Ahmad MafiDepartment of Radiation Oncology, Imam Hossein Hospital, Shaheed Beheshti Medical University, Tehran, Iran.
Payam AzadehDepartment of Radiation Oncology, Imam Hossein Hospital, Shaheed Beheshti Medical University, Tehran, Iran.
Maryam AghajanizadehDepartment of Radiation Oncology, Imam Hossein Hospital, Shaheed Beheshti Medical University, Tehran, Iran.
Afshin OstovarNational Cancer Control Secretariat, Ministry of Health and Medical Education, Tehran, Iran.
Alireza RaeisiDepartment of Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Reza MalekzadehDigestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Funding

World Health Organization 001
6 · The paper itself

Abstract

Cancer patients are at risk for severe complications or death from COVID-19 infection. Therefore, the need for routine COVID-19 testing in this population was evaluated. Between 1st August and 30th October 2020, 150 cancer patients were included. Symptoms of COVID-19 infection were evaluated. All eligible individuals went through RT-PCR and serological tests for COVID-19. At the same time, 920 non-cancer patients were recruited from a random sample of individuals who were subject to routine molecular and anti-body screening tests. Of 150 cancer patients, 7 (4.7%) were RT-PCR positive. Comorbidity made a significant difference in the RT-PCR positivity of cancer patients, 71.4% positive versus 25.8% negative (P-value = 0.02). The average age for negative and positive groups was 53.3 and 58.2 respectively (P-value = 0.01). No significant difference was observed between cancer and non-cancer patients regarding COVID-19 antibody tests. However, cancer patients were 3 times less likely to have a positive RT-PCR test result OR = 0.33 (CI: 0.15-0.73). The probability of cancer patients having a positive routine test was significantly lower than non-cancer patients, and the concept that all cancer patients should be routinely tested for COVID-19 may be incorrect. Nevertheless, there may be a subgroup of patients with comorbidities or older age who may benefit from routine COVID-19 testing. Importantly, these results could not be subjected to multivariate analysis.

Indexed as

NeoplasmsAdultAgedCOVID-19COVID-19 TestingDiagnostic Tests, RoutineFemaleHumansImmunoglobulin GImmunoglobulin MMaleMiddle AgedRetrospective StudiesImmunoglobulin GImmunoglobulin M

Identifiers

PMID34857785
PMCPMC8640074

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