Evidence map›Paper›PMID 34857776›Full record

ArticleScientific reports2021

Efficacy and immunogenicity of different BCG doses in BALB/c and CB6F1 mice when challenged with H37Rv or Beijing HN878.

Bhagwati Khatri, James Keeble, Belinda Dagg, Daryan A Kaveh, Philip J Hogarth, Mei Mei Ho

Abstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Novel Multistage SubunitVaccines · 2025
    Article
  2. Vaccination with aMicroorganisms · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. BCGΔBCG1419c increased memory CD8Scientific reports · 2022
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bhagwati KhatriBacteriology Division, National Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK. bhagwati.khatri@nibsc.org.
James KeebleBacteriology Division, National Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
Belinda DaggBacteriology Division, National Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.
Daryan A KavehDepartment of Bacteriology, Animal and Plant Health Agency, Addlestone, Surrey, KT15 3NB, UK.
Philip J HogarthDepartment of Bacteriology, Animal and Plant Health Agency, Addlestone, Surrey, KT15 3NB, UK.
Mei Mei HoBacteriology Division, National Institute for Biological Standards and Control, South Mimms, Potters Bar, Hertfordshire, EN6 3QG, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two strains of mice (BALB/c and CB6F1) were vaccinated with a range of Bacille Calmette-Guérin (BCG) Danish doses from 3 × 10

Indexed as

Immunogenicity, VaccineAnimalsBCG VaccineCD4-Positive T-LymphocytesDisease Models, AnimalInterferon-gammaInterleukin-2MiceMice, Inbred BALB CMice, Inbred StrainsMycobacterium tuberculosisTuberculosisTumor Necrosis Factor-alphaBCG VaccineInterferon-gammaInterleukin-2Tumor Necrosis Factor-alpha

Identifiers

PMID34857776
PMCPMC8639814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.