Evidence map›Paper›PMID 34857658›Full record

Trial reportJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Prognostic Value of Urokinase-Type Plasminogen Activator Receptor PET/CT in Head and Neck Squamous Cell Carcinomas and Comparison with

Louise M Risør, Malene M Clausen, Zaza Ujmajuridze, Mohammed Farhadi, Kim F Andersen, Annika Loft, Jeppe Friborg, Andreas Kjaer

Registry-linked trialOpen access · bronzeAbstract readClinical Trial, Phase II
In one paragraph

Trial report in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02965001 (Phase II Trial), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02965001 phase2completednot on this map

Phase II Trial: uPAR-PET/CT for Prognostication in Head- and Neck Cancer

TypeinterventionalSponsorRigshospitalet, DenmarkRan2016 to 2021Enrolled57ConditionsHead and Neck CancerArms68Ga-NOTA-AE105
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Review
  5. Radiopharmaceuticals and their applications in medicine.Signal transduction and targeted therapy · 2025
    Review
  6. Prospective phase II trial of [EJNMMI research · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Human antibody VFrontiers in oncology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Louise M RisørDepartment of Clinical Physiology, Nuclear Medicine, and PET and Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet, and Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Malene M ClausenDepartment of Clinical Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; and.
Zaza UjmajuridzeDepartment of Clinical Oncology, Næstved Hospital, Denmark.
Mohammed FarhadiDepartment of Clinical Oncology, Næstved Hospital, Denmark.
Kim F AndersenDepartment of Clinical Physiology, Nuclear Medicine, and PET and Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet, and Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Annika LoftDepartment of Clinical Physiology, Nuclear Medicine, and PET and Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet, and Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark.
Jeppe FriborgDepartment of Clinical Oncology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark; and.
Andreas KjaerDepartment of Clinical Physiology, Nuclear Medicine, and PET and Cluster for Molecular Imaging, Copenhagen University Hospital-Rigshospitalet, and Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark; akjaer@sund.ku.dk.
University of Copenhagen · DKNæstved Sygehus · DKRigshospitalet · DKCopenhagen University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this phase II clinical trial (NCT02965001) was to evaluate the prognostic value of urokinase-type plasminogen activator receptor (uPAR) PET/CT with the novel ligand

Indexed as

Fluorodeoxyglucose F18Head and Neck NeoplasmsGallium RadioisotopesHumansNeoplasm Recurrence, LocalPositron Emission Tomography Computed TomographyPrognosisProspective StudiesRadiopharmaceuticalsReceptors, Urokinase Plasminogen ActivatorSquamous Cell Carcinoma of Head and NeckFluorodeoxyglucose F18Gallium RadioisotopesRadiopharmaceuticalsReceptors, Urokinase Plasminogen Activator68Ga-NOTA-AE105head and neck cancerPET/CTprognosticationrisk stratificationurokinase-type plasminogen activator receptor

Identifiers

PMID34857658
PMCPMC9364350
OpenAlexW3217244680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.