Evidence map›Paper›PMID 34857648›Full record

ArticleLife science alliance2022

Artemisinin-independent inhibitory activity of

Kutub Ashraf, Shahin Tajeri, Christophe-Sébastien Arnold, Nadia Amanzougaghene, Jean-François Franetich, Amélie Vantaux, Valérie Soulard, Mallaury Bordessoulles, Guillaume Cazals, Teun Bousema and 9 more

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Perceptions and Acceptability ofHealthcare (Basel, Switzerland) · 2026
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  5. Medicinal plants as more sustainable therapeutic solutions:Global health economics and sustainability · 2025
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  6. The Antiviral and Antimalarial Prodrug Artemisinin from theCurrent issues in molecular biology · 2024
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  7. Transfection Models to InvestigatePathogens (Basel, Switzerland) · 2023
    Review
  8. Artemisinin as a therapeuticNatural product reports · 2023
    Review
  9. Article
  10. Knowledge about Asymptomatic Malaria and Acceptability of UsingInternational journal of environmental research and public health · 2023
    Article
  11. Expression of the Fab enzymes (Fab I and Fab Z) fromJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2023
    Article
  12. Anti-Frontiers in microbiology · 2023
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  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 6 institutions in 3 countries.

Kutub AshrafSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National pour la Recherche Scientifique (CNRS), Centre d'Immunologie et des Maladies Infectieuses, CIMI, Paris, France.ORCID 0000-0003-2527-0085
Shahin TajeriSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National pour la Recherche Scientifique (CNRS), Centre d'Immunologie et des Maladies Infectieuses, CIMI, Paris, France.ORCID 0000-0002-0482-1194
Christophe-Sébastien ArnoldApicoLipid Team, Institute for Advanced Biosciences, Centre National pour la Recherche Scientifique (CNRS) UMR5309, Université Grenoble Alpes, Institut National de la Santé et de la Recherche Médicale (INSERM) U1209, La Tronche, France.ORCID 0000-0002-2392-5837
Nadia AmanzougagheneSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National pour la Recherche Scientifique (CNRS), Centre d'Immunologie et des Maladies Infectieuses, CIMI, Paris, France.
Jean-François FranetichSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National pour la Recherche Scientifique (CNRS), Centre d'Immunologie et des Maladies Infectieuses, CIMI, Paris, France.
Amélie VantauxUnité d'Epidémiologie Moléculaire du Paludisme, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.ORCID 0000-0002-7945-961X
Valérie SoulardSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National pour la Recherche Scientifique (CNRS), Centre d'Immunologie et des Maladies Infectieuses, CIMI, Paris, France.
Mallaury BordessoullesSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National pour la Recherche Scientifique (CNRS), Centre d'Immunologie et des Maladies Infectieuses, CIMI, Paris, France.
Guillaume CazalsInstitut des Biomolécules Max Mousseron, UMR 5247, Université de Montpellier, Montpellier, France.
Teun BousemaDepartment of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands.
Geert-Jan van GemertDepartment of Medical Microbiology, Radboud University Nijmegen Medical Center, Nijmegen, Netherlands.ORCID 0000-0002-2740-5337
Roger Le GrandCommissariat à l'Energie Atomique et aux Energies Alternatives (CEA)-Université Paris Sud 11-INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA-HB), Infectious Disease Models and Innovative Therapies (IDMIT) Department, Institut de Biologie François Jacob (IBFJ), Direction de la Recherche Fondamentale (DRF), Fontenay-aux-Roses, France.
Nathalie Dereuddre-BosquetCommissariat à l'Energie Atomique et aux Energies Alternatives (CEA)-Université Paris Sud 11-INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA-HB), Infectious Disease Models and Innovative Therapies (IDMIT) Department, Institut de Biologie François Jacob (IBFJ), Direction de la Recherche Fondamentale (DRF), Fontenay-aux-Roses, France.
Jean-Christophe BaraleInstitut Pasteur, Pasteur International Network, Malaria Translational Research Pasteur International Unit, Phnom Penh, Cambodia and Paris, Paris, France.ORCID 0000-0002-1203-0376
Benoit WitkowskiUnité d'Epidémiologie Moléculaire du Paludisme, Institut Pasteur du Cambodge, Phnom Penh, Cambodia.
Georges SnounouCommissariat à l'Energie Atomique et aux Energies Alternatives (CEA)-Université Paris Sud 11-INSERM U1184, Immunology of Viral Infections and Autoimmune Diseases (IMVA-HB), Infectious Disease Models and Innovative Therapies (IDMIT) Department, Institut de Biologie François Jacob (IBFJ), Direction de la Recherche Fondamentale (DRF), Fontenay-aux-Roses, France.
Romain DuvalUniversité de Paris, Institut de Recherche pour le Développement (IRD), UMR 261 MERIT, Paris, France romain.duval@ird.fr.
Cyrille Y BottéApicoLipid Team, Institute for Advanced Biosciences, Centre National pour la Recherche Scientifique (CNRS) UMR5309, Université Grenoble Alpes, Institut National de la Santé et de la Recherche Médicale (INSERM) U1209, La Tronche, France romain.duval@ird.fr.ORCID 0000-0002-2245-536X
Dominique MazierSorbonne Université, Institut National de la Santé et de la Recherche Médicale (INSERM), Centre National pour la Recherche Scientifique (CNRS), Centre d'Immunologie et des Maladies Infectieuses, CIMI, Paris, France dominique.mazier@sorbonne-universite.fr.
Centre National de la Recherche Scientifique · FRUniversité Paris-Sud · FRInstitut Pasteur · FRRadboud University Nijmegen · NLUniversité de Montpellier · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artemisinin-based combination therapies (ACT) are the frontline treatments against malaria worldwide. Recently the use of traditional infusions from

Indexed as

AntimalarialsArtemisiaArtemisininsErythrocytesHepatocytesHumansLife Cycle StagesMalariaParasitic Sensitivity TestsPlant ExtractsPlasmodiumAntimalarialsArtemisininsPlant Extracts

Identifiers

PMID34857648
PMCPMC8675911
OpenAlexW3217204870

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.