Evidence map›Paper›PMID 34857581›Full record

ArticleBMJ open2021

Quantifying clinic transfers among people living with HIV in the Western Cape, South Africa: a retrospective spatial analysis.

Ana Lucia Espinosa Dice, Angela M Bengtson, Kevin M Mwenda, Christopher J Colvin, Mark N Lurie

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana Lucia Espinosa DiceDepartment of Biostatistics, Brown University School of Public Health, Providence, Rhode Island, USA.
Angela M BengtsonDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA.
Kevin M MwendaSpatial Structures in the Social Sciences (S4), Population Studies and Training Center (PSTC), Brown University, Providence, Rhode Island, USA.
Christopher J ColvinDivision of Social and Behavioural Sciences, School of Public Health and Family Medicine, University of Cape Town, Observatory, Western Cape, South Africa.
Mark N LurieDepartment of Epidemiology, Brown University School of Public Health, Providence, Rhode Island, USA mark_lurie@brown.edu.ORCID 0000-0002-3153-1715

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
Science/Technical CoreP2CHD041020 · NICHD · BROWN UNIVERSITY · PI ZHENCHAO QIAN · 2016 to 2026
$7.6M
Using Information to Align Services and Link and Retain Men in the HIV CascadeR01MH106600 · NIMH · UNIVERSITY OF CAPE TOWN · PI COLVIN, CHRISTOPHER JAMES, LURIE, MARK NATHAN · 2015 to 2019
$2.1M
Building Research in Inter-Disciplinary Gender and HIV through the Social Sciences (The BRIDGES Programme)D43TW011308 · FIC · UNIVERSITY OF CAPE TOWN · PI COLVIN, CHRISTOPHER JAMES · 2019 to 2023
$1.7M
An Implementation Science Approach to Monitoring Engagement in HIV CareR00MH112413 · NIMH · BROWN UNIVERSITY · PI BENGTSON, ANGELA · 2019 to 2021
$747k
FIC NIH HHS D43 TW011308NIAID NIH HHS P30 AI042853NICHD NIH HHS P2C HD041020NIMH NIH HHS R00 MH112413NIMH NIH HHS R01 MH106600
6 · The paper itself

Abstract

objectivesFor persons living with HIV (PLWH) in long-term care, clinic transfers are common and influence sustained engagement in HIV care, as they are associated with significant time out-of-care, low CD4 count, and unsuppressed viral load on re-entry. Despite the geospatial nature of clinic transfers, there exist limited data on the geospatial trends of clinic transfers to guide intervention development. In this study, we investigate the geospatial characteristics and trends of clinic transfers among PLWH on antiretroviral therapy (ART) in the Western Cape Province of South Africa.

designRetrospective spatial analysis.

settingPLWH who initiated ART treatment between 2012 and 2016 in South Africa's Western Cape Province were followed from ART initiation to their last visit prior to 2017. Deidentified electronic medical records from all public clinical, pharmacy, and laboratory visits in the Western Cape were linked across space and time using a unique patient identifier number.

participants4176 ART initiators in South Africa (68% women).

methodsWe defined a clinic transfer as any switch between health facilities that occurred on different days and measured the distance between facilities using geodesic distance. We constructed network flow maps to evaluate geospatial trends in clinic transfers over time, both for individuals' first transfer and overall.

resultsTwo-thirds of ART initiators transferred health facilities at least once during follow-up. Median distance between all clinic transfer origins and destinations among participants was 8.6 km. Participant transfers were heavily clustered around Cape Town. There was a positive association between time on ART and clinic transfer distance, both among participants' first transfers and overall.

conclusionThis study is among the first to examine geospatial trends in clinic transfers over time among PLWH. Our results make clear that clinic transfers are common and can cluster in urban areas, necessitating better integrated health information systems and HIV care.

Indexed as

Anti-HIV AgentsHIV InfectionsAmbulatory Care FacilitiesFemaleHumansMaleRetrospective StudiesSouth AfricaSpatial AnalysisAnti-HIV Agentsepidemiologyhiv & aids

Identifiers

PMID34857581
PMCPMC8640660

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.