Evidence map›Paper›PMID 34857554›Full record

ArticleBMJ open2021

Mixed-methods, descriptive and observational cohort study examining feeding and growth patterns among low birthweight infants in India, Malawi and Tanzania: the LIFE study protocol.

Linda Vesel, Lauren Spigel, Jnanindra Nath Behera, Roopa M Bellad, Leena Das, Sangappa Dhaded, Shivaprasad S Goudar, Gowdar Guruprasad, Sujata Misra, Sanghamitra Panda and 29 more

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04002908 (Low-birthweight Infant Feeding Exploration), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04002908 completednot on this map

Low-birthweight Infant Feeding Exploration

TypeobservationalSponsorHarvard School of Public Health (HSPH)Ran2019 to 2021Enrolled3,188ConditionsLow Birthweight, Pre-Term
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Observational
  2. Observational
  3. Article
  4. Observational
  5. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors at 13 institutions in 5 countries.

Linda VeselAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA lvesel@ariadnelabs.org.ORCID 0000-0003-3753-4172
Lauren SpigelAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.
Jnanindra Nath BeheraDepartment of Paediatrics, SCB Medical College and Hospital, Cuttack, Orissa, India.
Roopa M BelladJawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belgaum, Karnataka, India.
Leena DasDepartment of Paediatrics, SCB Medical College and Hospital, Cuttack, Orissa, India.
Sangappa DhadedJawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belgaum, Karnataka, India.
Shivaprasad S GoudarJawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belgaum, Karnataka, India.
Gowdar GuruprasadDepartment of Neonatology, JJM Medical College, Davangere, Karnataka, India.
Sujata MisraDepartment of Paediatrics, SCB Medical College and Hospital, Cuttack, Orissa, India.
Sanghamitra PandaDepartment of Obstetrics and Gynaecology, City Hospital, Cuttack, Orissa, India.
Latha G ShamanurDepartment of Paediatrics, SS Institute of Medical Sciences and Research Center, Davangere, Karnataka, India.
Sunil S VernekarJawaharlal Nehru Medical College, KLE Academy of Higher Education and Research, Belgaum, Karnataka, India.
Irving F HoffmanInstitute for Global Health and Infectious Diseases, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
Tisungane MvaloDepartment of Pediatrics, University of North Carolina Project Malawi, Lilongwe, Malawi.
Melda PhiriDepartment of Pediatrics, University of North Carolina Project Malawi, Lilongwe, Malawi.
Friday SaidiDepartment of Pediatrics, University of North Carolina Project Malawi, Lilongwe, Malawi.ORCID 0000-0003-1190-1499
Rodrick KisengeDepartment of Pediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Karim ManjiDepartment of Pediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Nahya SalimDepartment of Pediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Sarah SomjiDepartment of Pediatrics and Child Health, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Christopher R SudfeldDepartment of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Linda AdairDepartment of Nutrition, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, North Carolina, USA.
Bethany A CarusoHubert Department of Global Health, Emory University School of Public Health, Atlanta, Georgia, USA.
Christopher DugganCenter for Nutrition, Boston Children's Hospital, Boston, Massachusetts, USA.
Kiersten Israel-BallardMaternal, Newborn, Child Health and Nutrition Program, PATH, Seattle, Washington, USA.
Anne Cc LeeDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID 0000-0003-2654-9862
Stephanie L MartinDepartment of Nutrition, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, North Carolina, USA.
Kimberly L MansenMaternal, Newborn, Child Health and Nutrition Program, PATH, Seattle, Washington, USA.
Krysten NorthDepartment of Pediatric Newborn Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID 0000-0001-9283-4413
Melissa YoungHubert Department of Global Health, Emory University School of Public Health, Atlanta, Georgia, USA.
Emily BenottiAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.
Megan Marx DelaneyAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.
Eliza FishmanAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.
Katelyn FlemingAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.
Natalie HenrichAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.
Kate MillerAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.
Laura SubramanianAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.
Danielle E TullerAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.
Katherine Ea SemrauAriadne Labs, Harvard T.H. Chan School of Public Health / Brigham and Women's Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-8360-1391
Brigham and Women's Hospital · USJawaharlal Nehru Medical College · INMuhimbili University of Health and Allied Sciences · TZUniversity of North Carolina at Chapel Hill · USSriram Chandra Bhanja Medical College Hospital · INEmory University · USProgram for Appropriate Technology in Health · USUniversity of Malawi · MWBoston Children's Hospital · USCity Hospital · GBHarvard University · USJSS Medical College and Hospital · INShamnur Shivashankarappa Institute of Medical Sciences & Research Centre · IN

Funding

Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
The Roles of Perinatal Nutrition, Infection and Inflammation in the Neurodevelopment of Bangladeshi InfantsK23HD091390 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI LEE, ANNE SHEE CC · 2017 to 2021
$864k
NICHD NIH HHS K23 HD091390NICHD NIH HHS P2C HD050924
6 · The paper itself

Abstract

introductionEnding preventable deaths of newborns and children under 5 will not be possible without evidence-based strategies addressing the health and care of low birthweight (LBW, <2.5 kg) infants. The majority of LBW infants are born in low- and middle-income countries (LMICs) and account for more than 60%-80% of newborn deaths. Feeding promotion tailored to meet the nutritional needs of LBW infants in LMICs may serve a crucial role in curbing newborn mortality rates and promoting growth. The Low Birthweight Infant Feeding Exploration (LIFE) study aims to establish foundational knowledge regarding optimal feeding options for LBW infants in low-resource settings throughout infancy. METHODS AND ANALYSIS: LIFE is a formative, multisite, observational cohort study involving 12 study facilities in India, Malawi and Tanzania, and using a convergent parallel, mixed-methods design. We assess feeding patterns, growth indicators, morbidity, mortality, child development and health system inputs that facilitate or hinder care and survival of LBW infants. ETHICS AND DISSEMINATION: This study was approved by 11 ethics committees in India, Malawi, Tanzania and the USA. The results will be disseminated through peer-reviewed publications and presentations targeting the global and local research, clinical, programme implementation and policy communities. TRIAL REGISTRATION NUMBERS: NCT04002908 and CTRI/2019/02/017475.

Indexed as

Infant, Low Birth WeightBirth WeightChildCohort StudiesFemaleHumansInfantInfant, NewbornMalawiObservational Studies as TopicTanzaniaepidemiologyneonatologynutrition & dieteticspublic healthqualitative research

Identifiers

PMID34857554
PMCPMC8640640
OpenAlexW3214783223

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.