Evidence map›Paper›PMID 34857082›Full record

ReviewDeutsches Arzteblatt international2021

Acute Pulmonary Embolism–Its Diagnosis and Treatment From a Multidisciplinary Viewpoint.

Hannah C Kulka, Andreas Zeller, Jürgen Fornaro, Walter A Wuillemin, Stavros Konstantinides, Michael Christ

Open access · greenAbstract readReview
In one paragraph

Review in Deutsches Arzteblatt international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
70.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 90 citations in OpenAlex.

  1. Article
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  4. The Need for a Multidisciplinary Approach for Successful High-Risk Pulmonary Embolism Treatment.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Hannah C KulkaInstitute for Anesthesiology, Universiy Hospital Essen; Canton Hospital Basel-Land, University of Basel, Switzerland; Radiology, Canton Hospital Lucerne, Switzerland; Hematology, Canton Hospital Lucerne, Switzerland; School of Medicine, University of Mainz Emergency Center,; Canton Hospital Lucerne, Switzerland.
Andreas Zeller
Jürgen Fornaro
Walter A Wuillemin
Stavros Konstantinides
Michael Christ
Democritus University of Thrace · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPhysicians from many different specialties see patients suffering from acute pulmonary embolism (PE), which has an incidence of 39-115 cases per 100 000 persons per year. Because PE can be life-threatening, a rapid, targeted response is essential.

methodsThis review is based on pertinent publications retrieved by a selective literature search of international databases, with particular attention to current guidelines and expert opinions.

resultsWhenever PE is suspected, clinical assessment tools must be applied for risk stratification and diagnostic evaluation. The PERC (Pulmonary Embolism Rule-out Criteria) and the YEARS algorithm lead to more effective diagnosis. For hemodynamically unstable patients, bedside echocardiography is of high value and enables risk stratification. New oral anticoagulants have fewer hemorrhagic complications than vitamin K antagonists and are not inferior to them with respect to the risk of recurrent PE (hazard ratio 0.84-1.09). The duration of anticoagulation is set according to the risk of recurrence. Systemic thrombolysis is recommended for patients with a high-risk PE, in whom it significantly reduces mortality (odds ratio 0.53, number needed to treat 59). Surgical or interventional techniques can be considered if thrombolysis is contraindicated or unsuccessful.

conclusionNewly introduced diagnostic aids and algorithms simplify the diagnosis and treatment of acute PE while continuing to assure a high degree of patient safety.

Indexed as

Pulmonary EmbolismAcute DiseaseAnticoagulantsEchocardiographyFibrinolytic AgentsHumansAnticoagulantsFibrinolytic Agents

Identifiers

PMID34857082
PMCPMC8704819
OpenAlexW2094469287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.