Evidence map›Paper›PMID 34857047›Full record

ArticleSystematic reviews2021

Repetitive and restricted behaviours and anxiety in autism spectrum disorder: protocol for a systematic review and meta-analysis.

Tegan Sellick, Alexandra Ure, Katrina Williams

Open access · goldAbstract read
In one paragraph

Article in Systematic reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. A Factor-Analytic Approach for Psychometric Properties of the Repetitive Behaviors Questionnaire-3 (RBQ-3) for Turkish Population.Autism research : official journal of the International Society for Autism Research · 2026
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  11. Unlocking autism's complexity: theFrontiers in integrative neuroscience · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tegan SellickSchool of Psychology, Monash University, Wellington Road, Clayton, Victoria, 3800, Australia. teganjsellick@gmail.com.ORCID 0000-0003-0442-0048
Alexandra UreDepartment of Paediatrics & Education Research, Monash University, 246 Clayton Road, Clayton, Victoria, Australia. Alexandra.ure@monash.edu.
Katrina WilliamsDepartment of Paediatrics & Education Research, Monash University, 246 Clayton Road, Clayton, Victoria, Australia.
Royal Children's Hospital · AUMonash University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAutism spectrum disorder (ASD) is a neurodevelopmental disorder defined by persistent deficits in social functioning and the presence of restricted and repetitive behaviours (RRBs). RRBs refer to four subtypes of behaviour including repetitive movements, speech, or use of objects; insistence on sameness; restricted interests; and sensory processing abnormalities. Many individuals with ASD also experience anxiety, which compounds ASD-related difficulties and inhibits daily functioning. RRBs have been found to be positively associated with anxiety; however, our understanding of the interplay between RRB subtypes and anxiety remains unclear. Thus, the current review aims to clarify the association between RRBs and anxiety by conducting a systematic review and meta-analysis.

methodsTo identify relevant studies, we will search five databases: CINAHL Plus, Cochrane Central Register of Controlled Trials, Ovid MEDLINE, PsycINFO, and Scopus. Articles included in the review will have their titles, abstracts, and full texts reviewed by two independent authors and their methodological quality assessed via the modified Newcastle-Ottawa Scale. Random-effects meta-analyses will then be conducted to calculate the pooled association between RRB subtypes and anxiety. Sensitivity analyses will also be conducted to assess the potential impact of bias, missing data, outliers, and methodological differences on this relationship. Additionally, this review will collate the factors which may influence the anxiety-RRB relationship to help identify who is most vulnerable to developing anxiety. DISCUSSION: This will be the first review to examine the association between the four subtypes of RRBs and anxiety in individuals with ASD. Understanding this relationship, and the factors associated with this, may help clinicians understand the different underpinnings and presentations of anxiety within this population with potential implications for assessment and treatment. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020185434.

Indexed as

Autism Spectrum DisorderAnxietyHumansMeta-Analysis as TopicReview Literature as TopicStereotyped BehaviorSystematic Reviews as TopicAsperger’sHyperreactivity to sensory inputHyporeactivity to sensory inputMetanalysisObsessive-compulsive disorderQuantitative reviewWorry

Identifiers

PMID34857047
PMCPMC8638349
OpenAlexW3171584378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.