Evidence map›Paper›PMID 34856966›Full record

SynthesisBMC musculoskeletal disorders2021

Management of septic arthritis of the hip joint in adults. A systematic review of the literature.

Giovanni Balato, Vincenzo de Matteo, Tiziana Ascione, Roberto de Giovanni, Ernesto Marano, Maria Rizzo, Massimo Mariconda

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  8. Diagnostic work-up in periprosthetic joint infections of the knee: can the albumin-to-globulin ratio be a screening tool?Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2025
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  10. Open life sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Giovanni BalatoDepartment of Public Health, Orthopedic Unit, "Federico II" University, Via Sergio Pansini, 5, 80130, Naples, Italy. giovanni.balato@unina.it.
Vincenzo de MatteoDepartment of Public Health, Orthopedic Unit, "Federico II" University, Via Sergio Pansini, 5, 80130, Naples, Italy.
Tiziana AscioneService of Infectious Diseases, AORN Cardarelli Hospital, Naples, Italy.
Roberto de GiovanniDepartment of Public Health, Orthopedic Unit, "Federico II" University, Via Sergio Pansini, 5, 80130, Naples, Italy.
Ernesto MaranoDepartment of Public Health, Orthopedic Unit, "Federico II" University, Via Sergio Pansini, 5, 80130, Naples, Italy.
Maria RizzoDepartment of Public Health, Orthopedic Unit, "Federico II" University, Via Sergio Pansini, 5, 80130, Naples, Italy.
Massimo MaricondaDepartment of Public Health, Orthopedic Unit, "Federico II" University, Via Sergio Pansini, 5, 80130, Naples, Italy.
Federico II University Hospital · ITFatebenefratelli Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe septic arthritis of the hip is a complex condition characterized by a variety of clinical presentations, a challenging diagnosis and different surgical treatment options, including arthroscopy, resection arthroplasty and one and two-stage total hip replacement. Each technique reports variable results in terms of infection eradication rate. The aim of this systematic review is to compare the most relevant studies available in current literature and to assess if a better treatment outcome can be predicted based on the microbiology, history, and type of infection (active vs quiescent) of each case.

methodsA systematic review of the literature was performed in accordance with the PRISMA guidelines, including the studies dealing with the treatment of hip septic arthritis in adult patients. Electronic databases, namely the MEDLINE, Scopus, and Web of Science, were reviewed using a combination of following keywords "septic arthritis" AND "hip joint" OR "hip" AND "adult".

resultsThe total number of patients included in this review was 1236 (45% of which females), for 1238 hips. The most common pathogen isolated was Staphylococcus aureus in its Methicillin-sensitive variant ranging from 2 to 37% of cases. Negative cultures were the second most common finding. It was also differentiated the type of infection of the hip, 809 and 417 patients with active and quiescent hip infection, respectively, were analyzed. Eradication rates for two-stage revision arthroplasty ranged between 85 and 100%, for one-stage approach between 94 and 100%, while for arthroscopic debridement/lavage between 89 and 100%.

conclusionStaphylococcus aureus is the most common microorganism isolated followed by culture negative infections. Arthroscopic, one and two stage procedures can be effective in the treatment of hip septic arthritis when the indication is consistent with the type of infection retrieved. LEVEL OF EVIDENCE: IV, therapeutic study.

Indexed as

Arthritis, InfectiousArthroplasty, Replacement, HipStaphylococcal InfectionsArthroscopyDebridementFemaleHip JointHumansRetrospective StudiesTreatment OutcomeAdultHip jointInfectionSeptic arthritis

Identifiers

PMID34856966
PMCPMC8641144
OpenAlexW3216311330

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.