Evidence map›Paper›PMID 34856950›Full record

ArticleBMC pediatrics2021

Time to regain birth weight - a marker to predict the severity of retinopathy of prematurity?

Ajay Anvekar, Sam Athikarisamy, Shripada Rao, Andy Gill, Elizabeth Nathan, Dorota Doherty, Geoffrey Lam

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Time to regain birthweight and association with neurodevelopmental outcomes among extremely preterm newborns.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Trial
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Ajay AnvekarDepartment of Neonatal Paediatrics, Fiona Stanley hospital, Perth, Australia. ajayanvekar@yahoo.co.in.
Sam AthikarisamyDepartment of Neonatal Paediatrics, Perth Children's Hospital, Perth, Australia.
Shripada RaoDepartment of Neonatal Paediatrics, Perth Children's Hospital, Perth, Australia.
Andy GillDepartment of Neonatal Paediatrics, Perth Children's Hospital, Perth, Australia.
Elizabeth NathanWomen and Infants Research Foundation, King Edward Memorial Hospital for Women, Perth, Australia.
Dorota DohertyWomen and Infants Research Foundation, King Edward Memorial Hospital for Women, Perth, Australia.
Geoffrey LamDepartment of Ophthalmology, Perth Children's Hospital, Perth, Australia.
University of Western Australia · AUFiona Stanley Hospital · AUKing Edward Memorial Hospital · AUPerth Children's HospitalPrincess Margaret Hospital for Children · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPoor weight gain in the first few weeks of life has been studied as a predictor of retinopathy of prematurity (ROP). Our aim was to assess whether time taken to regain birthweight (BW) be used as an additional marker to identify infants with type 1 ROP.

methodsIn this retrospective study, preterm infants (< 27 weeks gestational age at birth) born during the period from 1/1/2010-31/12/2015 at a tertiary neonatal intensive care unit in Australia were included. Twenty-seven preterm infants with Type 1 ROP were identified. Controls (No ROP or ROP other than type 1) were matched with cases on gestational age at birth and BW (1:4 ratio). Data were collected from the database and medical records.

resultsThe median (IQR) gestational age for Type 1 ROP and control groups were 24 (24-26) and 25 (24-26) weeks respectively and median (IQR) BW for Type 1 ROP and control groups were 675 (635-810) and 773 (666-884) grams respectively. Preterm infants with Type 1 ROP were more likely to be small for gestational age (SGA) (18.5% vs 3.7%, p = 0.015) and had increased weeks on oxygen therapy (median 11.9 vs 9.1, p = 0.028). Time to regain BW was longer in preterm infants with type 1 ROP than controls but did not reach statistical significance (median 9 vs 7 days, OR 1.08, 95% CI 1.00-1.17, p = 0.059) adjusted for SGA and duration of oxygen therapy. The area under the curve from the time to regain BW model with adjustment for SGA and duration of oxygen therapy was 0.73 (95% CI 0.62-0.83).

conclusionWe hypothesize that time to regain BW has potential to aid prediction of Type 1 ROP and this warrants further investigation in a larger prospective study.

Indexed as

Retinopathy of PrematurityBirth WeightGestational AgeHumansInfantInfant, NewbornInfant, PrematureInfant, Very Low Birth WeightProspective StudiesRetrospective StudiesRisk FactorsBirth weightPretermRetinopathy of prematurity

Identifiers

PMID34856950
PMCPMC8638437
OpenAlexW3186675075

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.