Evidence map›Paper›PMID 34856849›Full record

ArticleBioengineered2022

New challenges in the use of nanomedicine in cancer therapy.

Mahmood Rasool, Arif Malik, Sulayman Waquar, Mahwish Arooj, Sara Zahid, Muhammad Asif, Sumaira Shaheen, Abrar Hussain, Hamid Ullah, Siew Hua Gan

Abstract read
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

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  17. Preparation of DOX-TPP/HA-ss-OA Nanoparticles, Investigation of Drug Release BehaviorCombinatorial chemistry & high throughput screening · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mahmood RasoolCenter of Excellence in Genomic Medicine Research, Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID 0000-0003-2997-5891
Arif MalikInstitute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore, Pakistan.ORCID 0000-0002-1894-6772
Sulayman WaquarInstitute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore, Pakistan.
Mahwish AroojUniversity College of Medicine and Dentistry (UCMD), Lahore, Pakistan.
Sara ZahidInstitute of Molecular Biology and Biotechnology (IMBB), The University of Lahore, Lahore, Pakistan.
Muhammad AsifDepartment of Biotechnology and ORIC, BUITEMS, Quetta, Pakistan.ORCID 0000-0003-4761-837X
Sumaira ShaheenCentre for Research in Molecular Medicine (CRiMM), The University of Lahore, Lahore, Pakistan.
Abrar HussainDepartment of Biotechnology, BUITEMS, Quetta, Pakistan.
Hamid UllahDepartment of Chemistry, BUITEMS, Quetta, Pakistan.
Siew Hua GanSchool of Pharmacy, Monash University Malaysia, Bandar Sunway, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanomedicines are applied as alternative treatments for anticancer agents. For the treatment of cancer, due to the small size in nanometers (nm), specific site targeting can be achieved with the use of nanomedicines, increasing their bioavailability and conferring fewer toxic side effects. Additionally, the use of minute amounts of drugs can lead to cost savings. In addition, nanotechnology is effectively applied in the preparation of such drugs as they are in nm sizes, considered one of the earliest cutoff values for the production of products utilized in nanotechnology. Early concepts described gold nanoshells as one of the successful therapies for cancer and associated diseases where the benefits of nanomedicine include effective active or passive targeting. Common medicines are degraded at a higher rate, whereas the degradation of macromolecules is time-consuming. All of the discussed properties are responsible for executing the physiological behaviors occurring at the following scale, depending on the geometry. Finally, large nanomaterials based on organic, lipid, inorganic, protein, and synthetic polymers have also been utilized to develop novel cancer cures.

Indexed as

NanostructuresNeoplasmsDrug Delivery SystemsHumansNanomedicineNanotechnologyactive targetingnanomaterialsNanomedicinenanoshellspassive targeting

Identifiers

PMID34856849
PMCPMC8805951

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.