Evidence map›Paper›PMID 34856826›Full record

Trial reportAcupuncture in medicine : journal of the British Medical Acupuncture Society2022

Feasibility and preliminary efficacy of acupuncture for angina in an underserved diverse population.

Holli A DeVon, Glorieuse Uwizeye, Hui Yan Cai, Adhir R Shroff, Joan E Briller, Amer Ardati, Debra Hoppensteadt, Lauren Rountree, Judith M Schlaeger

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Acupuncture in medicine : journal of the British Medical Acupuncture Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02914834 (Feasibility Testing of a Randomized Controlled Trial of Acupuncture to Improve Symptoms for Individuals With Stable Angina), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02914834 naterminatednot on this map

Feasibility Testing of a Randomized Controlled Trial of Acupuncture to Improve Symptoms for Individuals With Stable Angina (AIMS-A)

TypeinterventionalSponsorUniversity of Illinois at ChicagoRan2019 to 2020Enrolled27ConditionsAngina, Stable, Chest Pain, Microvascular Angina, Heart FailureArmsAcupuncture, Non-pain related video health education
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Electroacupuncture alleviates acute myocardial ischemic injury in mice by regulating the βAcupuncture in medicine : journal of the British Medical Acupuncture Society · 2024
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Holli A DeVonSchool of Nursing, University of California, Los Angeles, Los Angeles, CA, USA.
Glorieuse UwizeyeDepartment of Biobehavioral Nursing Science, College of Nursing, University of Illinois Chicago, Chicago, IL, USA.
Hui Yan CaiDepartment of Acupuncture and Oriental Medicine, National University of Health Sciences, Lombard, IL, USA.
Adhir R ShroffDepartment of Cardiology, College of Medicine, University of Illinois Chicago, Chicago, IL, USA.
Joan E BrillerDepartment of Cardiology, College of Medicine, University of Illinois Chicago, Chicago, IL, USA.
Amer ArdatiDepartment of Cardiology, College of Medicine, University of Illinois Chicago, Chicago, IL, USA.
Debra HoppensteadtDepartment of Pathology and Pharmacology, Loyola University Medical Center, Maywood, IL, USA.
Lauren RountreeSchool of Nursing, University of California, Los Angeles, Los Angeles, CA, USA.
Judith M SchlaegerDepartment of Human Development Nursing Science, College of Nursing, University of Illinois Chicago, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-3754-6176
University of Illinois Urbana-Champaign · USUniversity of California, Los Angeles · USUniversity of Illinois Chicago · USLoyola University Medical Center · USNational University of Health Sciences · US

Funding

Feasibility Testing of a Randomized Controlled Trial of Acupuncture to Improve Symptoms for Stable Angina (AIMS-A)R21NR017705 · NINR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DEVON, HOLLI A, SCHLAEGER, JUDITH MICHELLE · 2018 to 2019
$440k
NINR NIH HHS R21 NR017705
6 · The paper itself

Abstract

purposeStable angina is ischemic chest pain on exertion or with emotional stress. Despite guideline-directed therapy, up to 30% of patients have suboptimal pain relief. The aims of this study were to: (1) determine the feasibility and acceptability of a randomized controlled trial (RCT) of acupuncture; and (2) evaluate preliminary efficacy of acupuncture with respect to reduction of pain and increased functional status and health-related quality of life (HRQoL).

methodsParticipants with stable angina for ⩾1 month received either a standardized acupuncture protocol, twice per week for 5 weeks, or an attention control protocol. Measures included the McGill Pain Questionnaire (average pain intensity (API), pain now) and the Seattle Angina Questionnaire-7 (functional status, symptoms, and HRQoL). Feasibility was defined as ⩾80% recruitment, ⩾75% retention following enrollment, and ⩾80% completion. Descriptive statistics and mixed-effects linear regression were used for analysis.

resultsThe sample (n = 24) had a mean age of 59 ± 12 years, was predominantly female (63%), and represented minority groups (8% White, 52% Black, 33% Hispanic, and 8% Other). Feasibility was supported by 79% retention and 89% completion rates. The recruitment rate (68%) was slightly lower than expected. Acceptability scores were 87.9% for the acupuncture group and 51.7% for the control group. Outcomes were significantly better for the acupuncture versus control groups (API, b = -2.1 (1.1), p = 0.047; functional status, b = 27.6 (7.2), p < 0.001; and HRQoL, b = 38.8 (11.9), p = 0.001). CONCLUSIONS AND IMPLICATIONS: Acupuncture was feasible and acceptable in our diverse sample. We were slightly under the recruitment target of 80%, but participants who started the study had a high likelihood of completing it. Acupuncture shows promise for stable angina, but its effectiveness needs to be confirmed by a larger, adequately powered RCT. TRIAL REGISTRATION NUMBER: NCT02914834 (ClinicalTrials.gov).

Indexed as

Acupuncture TherapyAgedFeasibility StudiesFemaleHumansMiddle AgedPain MeasurementQuality of LifeTreatment Outcomeacupunctureintegrative therapyischemic heart diseasestable angina

Identifiers

PMID34856826
PMCPMC8881402
OpenAlexW3217656334

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.