Evidence map›Paper›PMID 34856552›Full record

ArticleDementia and geriatric cognitive disorders2021

Mortality Risk within 14 Days after Coronavirus Disease 2019 Diagnosis in Dementia Patients: A Nationwide Analysis.

Yi-Jun Kim, Yongho Jee, Sholhui Park, Eun-Hee Ha, Inho Jo, Hyang Woon Lee, Myung Seon Song

Open access · bronzeAbstract read
In one paragraph

Article in Dementia and geriatric cognitive disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yi-Jun KimInstitute of Convergence Medicine, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Yongho JeeAdvanced Biomedical Research Institute, Ewha Womans University Seoul Hospital, Seoul, Republic of Korea.
Sholhui ParkDepartment of Laboratory Medicine, Ewha Womans University Seoul Hospital, Seoul, Republic of Korea.
Eun-Hee HaDepartment of Occupational and Environmental Medicine, Ewha Womans University College of Medicine, Seoul, Republic of Korea.
Inho JoSystem Health Science & Engineering, Ewha Womans University, Seoul, Republic of Korea.
Hyang Woon LeeSystem Health Science & Engineering, Ewha Womans University, Seoul, Republic of Korea.
Myung Seon SongDepartment of Psychiatry, Keyo Hospital, Uiwang, Republic of Korea.
Ewha Womans University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe study evaluated the increased mortality risk within 14 days of coronavirus disease 2019 (COVID-19) diagnosis in dementia patients.

methodsThis retrospective study was conducted from February to April 2020 using the COVID-19 patients' database from the Korea Disease Control and Prevention Agency. The risk factors for early death within 14 days were determined using generalized logistic regression performed in a stepwise manner. Dementia patients diagnosed with COVID-19 were used for the study. The propensity score-matched cohort was included as controls. The differences in mortality within 14 days after COVID-19 diagnosis between the dementia patients and controls were evaluated.

resultsWe enrolled 5,349 COVID-19 patients from the database; 224 had dementia as comorbidity. The mortality rate within 14 days after COVID-19 diagnosis in dementia patients and the controls was 23.7% versus 1.7%, respectively, before propensity score matching (PSM) (p < 0.001), and 23.7% versus 9.2% after PSM (p < 0.001). The hazard ratio (HR) for mortality within 14 days in COVID-19 patients with dementia was significant even after PSM (HR 5.104, 95% confidence interval 2.889-5.673, p < 0.001). The survival curve of dementia patients was steeply inclined within 14 days after COVID-19 diagnosis, resulting in 70.7% of all deaths in dementia patients.

conclusionsCOVID-19 patients with dementia had a higher risk of early death within 14 days. Thus, prompt intervention is necessary for dementia patients after COVID-19 diagnosis.

Indexed as

COVID-19DementiaCOVID-19 TestingHumansRetrospective StudiesRisk FactorsSARS-CoV-2COVID-19DementiaEarly deathGeneral logistic regressionPropensity score matching

Identifiers

PMID34856552
PMCPMC8805064
OpenAlexW3216583007

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.