ArticleCarbohydrate research2022
Streamlined access to carbohydrate building blocks: Methyl 2,4,6-tri-O-benzyl-α-d-glucopyranoside.
Article in Carbohydrate research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Application of the Hydrogen-Bond-Mediated Aglycone Delivery (HAD) Reaction to the Synthesis of α- and β-Linked 2-Azido-2-deoxyglucosides.Chemistry, an Asian journal · 2026Article
- Article
- Enhanced experimental set-up for HPLC-based automated synthesis and purification of carbohydrate building blocks.Carbohydrate research · 2025Article
- Ferric Chloride Promoted Glycosidation of Alkyl Thioglycosides.Molecules (Basel, Switzerland) · 2024Article
- Expedient Synthesis of Superarmed Glycosyl Donors via Oxidative Thioglycosidation of Glycals.Synthesis · 2024Article
- Activation of thioglycosides under mild alkylation conditions.Carbohydrate research · 2023Article
- Activation of Thioglycosides with Copper(II) Bromide.Molecules (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Presented herein is an improved synthesis of a common 3-OH glycosyl acceptor. This compound is a building block that is routinely synthesized by many research groups to be used in glycosylation refinement studies. The only known direct synthesis by Koto lacks regioselectivity and relies on chromatography separation using hazardous solvents. Our improved synthetic approach relies on Koto's selective benzylation protocol, but it is followed by acylation-purification-deacylation sequence. Although this approach involves additional manipulations, it provides consistent results and is superior to other indirect strategies. Also obtained, albeit in minor quantities, is 4-OH acceptor, another common building block.
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Registered trials
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