SynthesisNeuroscience and biobehavioral reviews2022
Reading intervention and neuroplasticity: A systematic review and meta-analysis of brain changes associated with reading intervention.
Synthesis in Neuroscience and biobehavioral reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Efficacy of neurofeedback in the treatment of Dyslexia: a systematic review.Annals of dyslexia · 2026Pooled it
- Examination of common and unique brain regions for atypical reading and math: a meta-analysis.Cerebral cortex (New York, N.Y. : 1991) · 2023Pooled it
- Developmental Reading-Network Reorganization in Developmental Dyslexia: A Neuroplasticity Framework.Brain sciences · 2026Review
- Experience-dependent cortical plasticity in response to formal schooling: Effects on networks for reading and mathematics.Developmental cognitive neuroscience · 2026Article
- The effect of binaural beats on phonological awareness and cortical connectivity in dyslexic children.Scientific reports · 2026Article
- Neurodevelopmental disorders in children: the role of MRI in early detection and intervention planning.Frontiers in neuroscience · 2026Review
- The balance between stability and plasticity of the visual word form area in dyslexia.Nature communications · 2025Article
- Leveraging AI-Driven Neuroimaging Biomarkers for Early Detection and Social Function Prediction in Autism Spectrum Disorders: A Systematic Review.Healthcare (Basel, Switzerland) · 2025Review
- Brain Changes Following Two Reading Interventions in Chinese Children With Reading Disability.Developmental science · 2025Article
- Resting-State Functional MRI in Dyslexia: A Systematic Review.Biomedicines · 2025Review
- Phonological decoding ability is associated with fiber density of the left arcuate fasciculus longitudinally across reading development.Developmental cognitive neuroscience · 2025Article
- Neurostimulation improves reading and alters communication within reading networks in dyslexia.Annals of the New York Academy of Sciences · 2025Article
- Impact of COVID-19 School Closures on White Matter Plasticity in the Reading Network.Neurobiology of language (Cambridge, Mass.) · 2025Article
- Neuronal Mechanisms of Reading Informational Texts in People with Different Levels of Mental Resilience.Brain sciences · 2024Article
- Short-term number sense training recapitulates long-term neurodevelopmental changes from childhood to adolescence.Developmental science · 2024Article
- Alterations in neural activation in the ventral frontoparietal network during complex magnocellular stimuli in developmental dyslexia associated with READ1 deletion.Behavioral and brain functions : BBF · 2024Article
- Reaching Students with Reading Disabilities During the Summer.Policy insights from the behavioral and brain sciences · 2024Article
- Will you read how I will read? Naturalistic fMRI predictors of emergent reading.Neuropsychologia · 2024Article
- White matter microstructural plasticity associated with educational intervention in reading disability.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Age-related changes in individuals with and without reading disability: Behavioral and fMRI evidence.Imaging neuroscience (Cambridge, Mass.) · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Behavioral research supports the efficacy of intervention for reading disability, but the brain mechanisms underlying improvement in reading are not well understood. Here, we review 39 neuroimaging studies of reading intervention to characterize links between reading improvement and changes in the brain. We report evidence of changes in activation, connectivity, and structure within the reading network, and right hemisphere, frontal and sub-cortical regions. Our meta-analysis of changes in brain activation from pre- to post- reading intervention in eight studies did not yield any significant effects. Methodological heterogeneity among studies may contribute to the lack of significant meta-analytic findings. Based on our qualitative synthesis, we propose that brain changes in response to intervention should be considered in terms of interactions among distributed cognitive, linguistic and sensory systems, rather than via a "normalized" vs. "compensatory" dichotomy. Further empirical research is needed to identify effects of moderating factors such as features of intervention programs, neuroimaging tasks, and individual differences among participants.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.