Evidence map›Paper›PMID 34856130›Full record

ArticleNeuron2021

Excessive mitophagy for anxiety.

Hongsheng Wang, Wen-Cheng Xiong, Lin Mei

Abstract readComment
PubMed Publisher
In one paragraph

Article in Neuron, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Mitophagy in kidney transplantation ischemia-reperfusion injury.International urology and nephrology · 2026
    Review
  2. Neurobiology of stress · 2025
    Review
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hongsheng WangDepartment of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA.
Wen-Cheng XiongDepartment of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA.
Lin MeiDepartment of Neurosciences, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA; Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA. Electronic address: lin.mei@case.edu.
University School · USLouis Stokes Cleveland VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Neuron, Duan et al. (2021) identified excessive mitophagy in BLA neurons synapsing onto adBNST neurons as a mechanism for reduced neurotransmission and social defeat-induced anxiety-like behaviors.

Indexed as

AnxietyMitophagyAnxiety DisordersHumansNeuronsSynaptic Transmission

Identifiers

PMID34856130
OpenAlexW3216392106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.