Evidence map›Paper›PMID 34855905›Full record

ArticlePloS one2021

Prevalence and clinical profile of glaucoma patients in rural Nigeria-A hospital based study.

Ngozika E Ezinne, Chukwuebuka S Ojukwu, Kingsley K Ekemiri, Obinna F Akano, Edgar Ekure, Uchechukwu Levi Osuagwu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 6 countries.

Ngozika E EzinneDepartment of Clinical Surgical Sciences, Optometry Unit, University of the West Indies, St Augustine Campus, Trinidad and Tobago.
Chukwuebuka S OjukwuDepartment of Optometry, Madonna University, Elele campus, Okija, Nigeria.
Kingsley K EkemiriDepartment of Clinical Surgical Sciences, Optometry Unit, University of the West Indies, St Augustine Campus, Trinidad and Tobago.ORCID 0000-0003-3881-7502
Obinna F AkanoI and Eye Optometry, Bronx, New York, New York, United States of America.
Edgar EkureDepartment of Biomedicine, Salus University, Elkins Park, Pennsylvania, United States of America.
Uchechukwu Levi OsuagwuTranslational Health Research Institute (THRI), School of Medicine, Western Sydney University, Campbelltown, NSW, Australia.ORCID 0000-0002-1727-6914
University of the West Indies · TTOxford Brookes University · GBSalus University · USSUNY College of Optometry · USTranslational Research Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo determine the prevalence and clinical presentation of participants with glaucoma attending a public eye care facility in Nigeria.

methodHospital based retrospective study of glaucoma participants aged 50 years and above seen over a 5-year period. Descriptive statistics summarized the demographic, clinical characteristics and treatment of the participants and determined the association of variables with gender and age. Prevalence of the glaucoma by type, and their 95% confidence intervals (CI) were also calculated.

resultOf the 5482 case files that were reviewed, 995 (18.15%, 95% Cl 17.15-19.19%) had glaucoma particularly primary open angle glaucoma (11.55%, 95%CI 10.73-12.42%) and were mostly females (564, 56.7%) aged 69 ± 12 years (range, 50-103 years). In contrast to other glaucoma types, the prevalence of primary angle closure glaucoma (3.68, 95%CI 3.22-4.22) increased by 15% over 5 years. The mean intraocular pressure ranged from 15-50 mmHg but higher in females than males (27.8 ± 6.1mmHg versus 26.6 ± 6.0 mmHg, P <0.05) who had comparable VA (0.58 ± 0.4 Log MAR) and cup-disc ratios (P >0.05). On presentation, the glaucoma hemi field test (GHFT) was outside the normal limits in 45.5% and 54.5% of males and females, respectively. The type of visual field defect was associated with glaucoma type (P = 0.047). Arcuate scotoma was most common (35.5%) across glaucoma types, paracentral scotoma more common in Secondary glaucoma while Seidel scotoma was highest in NTG (19.3%). Beta-blocker was the mainstay of management (42.2%) but more likely to be prescribed to males while more females received carbonic anhydrase inhibitors.

conclusionsThe high prevalence of glaucoma in older people remains a public health problem in Nigeria. The fact that about half of the participants presented with visual field defect suggests there is a need for public health messages to emphasize on early glaucoma screening, detection and management.

Indexed as

Intraocular PressureVisual FieldsAgedAged, 80 and overAge FactorsFemaleGlaucomaHumansMaleMiddle AgedNigeriaPrevalenceRetrospective StudiesSex Factors

Identifiers

PMID34855905
PMCPMC8639068
OpenAlexW3217562506

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.