ArticlePloS one2021
Antifungal activity of volatile compounds generated by endophytic fungi Sarocladium brachiariae HND5 against Fusarium oxysporum f. sp. cubense.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 48 citations in OpenAlex.
- Multifunctional biological roles of Fusaric acid and its derivatives in the Diverse Kingdoms of Life: Insights from More Than Nine Decades of Research.Pharmaceutical research · 2026Review
- Morphological and genetic characterization of novelMicrobiology spectrum · 2026Article
- Cross-talk within plant niches: endophytic and arbuscular mycorrhizal fungi for sustainable crop production.FEMS microbiology reviews · 2026Review
- Antifungal activity of volatile organic compounds produced byFrontiers in microbiology · 2026Article
- 4-Vinylguaiacol in Citri Reticulatae 'Chachiensis' Pericarpium Volatile Oil: A Microbial-Mediated Aging Marker Enhances Glucose Metabolism.Foods (Basel, Switzerland) · 2025Article
- 3-Methyl pentanoic acid suppress gray mold disease potentially targeting cell-wall integrity (CWI) and mitogen-activated protein kinase (MAPK) pathways in Botrytis cinerea.BMC microbiology · 2025Article
- Development of an Application Method for Volatile Compounds Derived from Mushroom Fungi Beds as Plant Growth-Promoting Biostimulants.Methods and protocols · 2025Article
- Screening, Diversity, and Characterization of Fungal Endophytes Isolated From the HalophytePlant direct · 2025Article
- Endophytic Fungi: A Treasure Trove of Antifungal Metabolites.Microorganisms · 2024Review
- Characterization and identification of antimicrobial compounds from endophytic Fusarium incarnatum isolated from Cymbidium orchids.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Endophytic Fungi Volatile Organic Compounds as Crucial Biocontrol Agents Used for Controlling Fruit and Vegetable Postharvest Diseases.Journal of fungi (Basel, Switzerland) · 2024Review
- LC-MS based metabolomics identification of natural metabolites againstFrontiers in plant science · 2024Article
- Article
- Identification of Lipopeptide Iturin A Produced byFoods (Basel, Switzerland) · 2022Article
- Endophytes and their potential in biotic stress management and crop production.Frontiers in microbiology · 2022Review
- Overview of biofertilizers in crop production and stress management for sustainable agriculture.Frontiers in plant science · 2022Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The soil-born filamentous fungal pathogen Fusarium oxysporum f. sp. cubense (FOC), which causes vascular wilt disease in banana plants, is one of the most economically important Fusarium species. Biocontrol using endophytic microorganisms is among the most effective methods for controlling banana Fusarium wilt. In this study, volatile organic compounds (VOCs) showed strong antifungal activity against FOC. Seventeen compounds were identified from the VOCs produced by endophytic fungi Sarocladium brachiariae HND5, and three (2-methoxy-4-vinylphenol, 3,4-dimethoxystyrol and caryophyllene) showed antifungal activity against FOC with 50% effective concentrations of 36, 60 and 2900 μL/L headspace, respectively. Transmission electron microscopy (TEM) and double fluorescence staining revealed that 2-methoxy-4-vinylphenol and 3,4-dimethoxystyrol damaged the plasma membranes, resulting in cell death. 3,4-dimethoxystyrol also could induce expression of chitin synthases genes and altered the cell walls of FOC hyphae. Dichloro-dihydro-fluorescein diacetate staining indicated the caryophyllene induced accumulation of reactive oxygen species (ROS) in FOC hyphae. FOC secondary metabolism also responded to active VOC challenge by producing less fusaric acid and expressions of genes related to fusaric acid production were interrupted at sublethal concentrations. These findings indicate the potential of S. brachiariae HND5 as a biocontrol agent against FOC and the antifungal VOCs as fumigants.
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