Evidence map›Paper›PMID 34855854›Full record

Observational studyPloS one2021

Trend in blood lead levels in Taiwanese adults 2005-2017.

Chun-Wan Fang, Hsiao-Chen Ning, Ya-Ching Huang, Yu-Shao Chiang, Chun-Wei Chuang, I-Kuan Wang, Nai-Chia Fan, Cheng-Hao Weng, Wen-Hung Huang, Ching-Wei Hsu and 1 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chun-Wan FangDepartment of Laboratory Medicine, Chang Gung Memorial Hospital, Taoyuan, Linkou, Taiwan.
Hsiao-Chen NingDepartment of Medical Biotechnology and Laboratory Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ya-Ching HuangDepartment of Laboratory Medicine, Chang Gung Memorial Hospital, Taoyuan, Linkou, Taiwan.
Yu-Shao ChiangDepartment of Laboratory Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan.
Chun-Wei ChuangDepartment of Laboratory Medicine, Chang Gung Memorial Hospital, Taoyuan, Linkou, Taiwan.
I-Kuan WangDepartment of Nephrology, China Medical University Hospital, Taichung, Taiwan.
Nai-Chia FanDivision of Pediatric General Medicine, Department of Pediatrics, Chang Gung Memorial Hospital, Linkou, Taiwan.
Cheng-Hao WengCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Wen-Hung HuangCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Ching-Wei HsuCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.
Tzung-Hai YenCollege of Medicine, Chang Gung University, Taoyuan, Taiwan.ORCID 0000-0002-0907-1505

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the trend of blood lead levels (BLLs) in Taiwanese adults and analyzed the variations in the BLL between Linkou (northern) and Kaohsiung (southern) hospital branches. Between 2005 and 2017, 3,804 adult participants received blood lead tests at the Linkou (n = 2,674) and Kaohsiung (n = 1,130) branches of Chang Gung Memorial Hospital. The geometric mean of BLL was 2.77 μg/dL. The adult participants from the Kaohsiung branch were not only age older (49.8±14.1 versus 39.4±14.2 years; P<0.001) and male predominant (65.8 versus 41.7%; P<0.001) but also showed a higher BLL (4.45±3.93 versus 2.82±2.42 μg/dL; P<0.001) and lower estimated glomerular filtration rate (87.62±25.94 versus 93.67±23.88; P<0.001) than those from the Linkou branch. Multivariable logistic regression analysis revealed that the Kaohsiung branch [odds ratio (OR): 7.143; 95% confident interval (CI): 5.682-8.929; P<0.001], older age (OR: 1.008; 95% CI: 1.000-1.015; P = 0.043) and reduced estimated glomerular filtration rate (OR: 1.009; 95% CI: 1.004-1.014; P = 0.001) were significant predictors for BLL > 5 μg/dL. Therefore, this study confirmed a continuous decreasing trend in the BLL in Taiwan after banning leaded petrol in 2000.

Indexed as

AdolescentAdultEnvironmental ExposureFemaleFollow-Up StudiesHumansLeadLead PoisoningMaleMiddle AgedPrognosisRetrospective StudiesTaiwanYoung AdultLead

Identifiers

PMID34855854
PMCPMC8638909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.