Evidence map›Paper›PMID 34855102›Full record

ArticleMycopathologia2022

A Chronic Autochthonous Fifth Clade Case of Candida auris Otomycosis in Iran.

Fatemeh Safari, Mahboobeh Madani, Hamid Badali, Amir-Abbas Kargoshaie, Hamed Fakhim, Majid Kheirollahi, Jacques F Meis, Hossein Mirhendi

Abstract read
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In one paragraph

Article in Mycopathologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Microbiology spectrum · 2026
    Article
  4. Review
  5. UnderstandingJournal of medical microbiology · 2026
    Review
  6. Article
  7. Molecular Identification ofAdvanced biomedical research · 2025
    Article
  8. A simple and sensitive test forJournal of clinical microbiology · 2024
    Article
  9. Emergence of the novel sixthMicrobiology spectrum · 2024
    Article
  10. Yeast species in the respiratory samples of COVID-19 patients; molecular tracking ofFrontiers in cellular and infection microbiology · 2024
    Article
  11. An Autochthonous SusceptibleJournal of fungi (Basel, Switzerland) · 2023
    Article
  12. Candida auris: a global pathogen that has taken root in ColombiaBiomedica : revista del Instituto Nacional de Salud · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Strategies to Prevent Transmission ofCurrent fungal infection reports · 2023
    Review
  17. Confirmation of fifthEmerging microbes & infections · 2022
    Article
  18. Article
  19. Population genomic analyses reveal evidence for limited recombination in the superbugComputational and structural biotechnology journal · 2022
    Article
  20. Diagnostic Allele-Specific PCR for the Identification ofJournal of fungi (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fatemeh SafariDepartment of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran.
Mahboobeh MadaniDepartment of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran.
Hamid BadaliInvasive Fungi Research Center, Communicable Diseases Institute, Mazandaran University of Medical Sciences, Sari, Iran.
Amir-Abbas KargoshaieDepartment of Otolaryngology, School of Medicine, Al-Zahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.
Hamed FakhimInfectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Majid KheirollahiDepartment of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Jacques F MeisDepartment of Medical Microbiology and Infectious Diseases, Canisius-Wilhelmina Hospital, Nijmegen, The Netherlands.
Hossein MirhendiDepartment of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran. s.h.mirhendi@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candida auris, a multidrug-resistant nosocomial pathogen, has emerged globally with high morbidity and mortality among immunocompromised individuals and COVID19 hospitalized patients. Five major clades of C. auris have been previously described. The fifth clade is exclusively found in Iran where C. auris isolates are genetically distinct from other clades by > 200,000 single-nucleotide polymorphisms. The origin of C. auris remains unclear, and limited clinical data are available at present regarding clade V infection or colonization. Herein, another case of otomycosis in Iran caused by an isolate of C. auris belonging to the fifth clade is reported. Genotyping revealed that the obtained C. auris isolate from Isfahan clustered with earlier clade V isolates from Babol, cities around 600 km separated, which indicates that C. auris clade V is established in Iran. C. auris is thought to exist more commonly in Iran, given that limited diagnostic capacity in the country has probably curbed the identification of more C. auris cases. Therefore, surveillance of the environment, patients and healthcare facilities in different geographical regions in Iran is urgently required.

Indexed as

CandidiasisCOVID-19OtomycosisAntifungal AgentsCandidaCandida aurisHumansIranSARS-CoV-2Antifungal AgentsCandida aurisFifth cladeIranOtomycosis

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.