Evidence map›Paper›PMID 34855093›Full record

ArticleBulletin of experimental biology and medicine2021

Lymphocyte Index of Peripheral Blood in Rats at Different Stages of the Post-Stress Period under Conditions of Antigenic Exposure and Injection of Lipopolysaccharide.

I V Alekseeva, E V Nikenina, A Yu Abramova, A Yu Kozlov, E V Koplik, S S Pertsov

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Article in Bulletin of experimental biology and medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 62% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

I V AlekseevaP. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia. kiv24irina@mail.ru.
E V NikeninaP. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia.
A Yu AbramovaP. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia.
A Yu KozlovP. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia.
E V KoplikP. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia.
S S PertsovP. K. Anokhin Research Institute of Normal Physiology, Moscow, Russia.
Institute of Normal Physiology named after P.K. Anokhin · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Changes in the Shaganin lymphocyte index (ratio of the number of lymphocytes to segmented neutrophils) in the peripheral blood of rats after intraperitoneal administration of LPS (100 μg/kg) at the end of a single stress exposure in a model of 24-h restraint stress were studied. The lymphocyte index was analyzed 3 h later, on the 1st and 8th days after the stress load. Immobilization was accompanied by a decrease in this parameter 3 h after exposure. One day after the stress load, an increase in the lymphocyte index was noted, which remained on the 8th day of observation. LPS injection did not affect the changes in this parameter caused by 24-h immobilization on the 1st and 8th days of the study, but prevented a pronounced increase in the lymphocyte index on the 1st day after the stress load. The data obtained expand the existing scientific understanding of the specificity of the involvement of immunomodulatory substances in the implementation of adaptive-compensatory processes in mammals under conditions of emotional stress.

Indexed as

AnimalsImmobilizationInjections, IntraperitonealLeukocyte CountLipopolysaccharidesLymphocyte CountLymphocytesNeutrophilsRatsRats, WistarStress, PsychologicalLipopolysaccharides24-h immobilizationlipopolysaccharidelymphocyte indexratsstress load

Identifiers

PMID34855093
OpenAlexW3193879236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.