Evidence map›Paper›PMID 34854927›Full record

ArticleAbdominal radiology (New York)2022

Interobserver variability in MRI measurements of mesorectal invasion depth in rectal cancer.

Mariana M Chaves, Henrique Donato, Nuno Campos, David Silva, Luís Curvo-Semedo

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Article in Abdominal radiology (New York), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Mariana M ChavesDepartment of Radiology, Hospital do Divino Espírito Santo de Ponta Delgada EPE, Ponta Delgada, Portugal. m.m.chvs@gmail.com.ORCID 0000-0002-4842-1299
Henrique DonatoDepartment of Radiology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
Nuno CamposDepartment of Radiology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
David SilvaDepartment of Radiology, Hospital do Divino Espírito Santo de Ponta Delgada EPE, Ponta Delgada, Portugal.
Luís Curvo-SemedoDepartment of Radiology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.ORCID 0000-0002-6441-227X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

proposeTo assess the interobserver variability in MRI measurements of mesorectal invasion depth (MID) in rectal adenocarcinomas primarily staged as T3, by determining the level of interobserver agreement in the differentiation of individual T3 substages and of T3a-b vs. T3c-d disease, between readers with different levels of expertise.

methodsA retrospective analysis of 60 patients classified by MRI as having T3 rectal cancers was performed. Each patient underwent MR examination in a 1.5 T machine and the standard imaging protocol included a high-resolution axial T2-weighted sequence in which the measurements were determined by independent radiologists (readers A and B, with 15 years and 1 year of experience, respectively). The rectum was further divided into quadrants and each reader selected the quadrant where the measurement was taken. The patients were grouped according to the MID (T3a < 1 mm; T3b 1-5 mm; T3c > 5-15 mm; T3d > 15 mm) and the interobserver reliability was tested using Cohen's kappa.

resultsPopulation included 40 males and 20 females with a median age of 65.9 years. Interobserver agreement on individual substage differentiation (T3 a, b, c and d) was moderate (K = 0.428) and in the quadrant evaluation the level of agreement was also moderate (K = 0.414). Nevertheless, the interobserver reliability for the differentiation between stages T3a-b vs. T3c-d was substantial (K = 0.697).

conclusionsThere is no considerable interobserver variability when distinguishing T3a-b from T3c-d tumors, regardless of the quadrant where the MID is measured. Therefore, assessment of MID, for that purpose, is a reproducible MR parameter, irrespectively of the readers' experience.

Indexed as

Rectal NeoplasmsAgedFemaleHumansMagnetic Resonance ImagingMaleNeoplasm InvasivenessNeoplasm StagingObserver VariationReproducibility of ResultsRetrospective StudiesMagnetic resonance imagingMesorectal invasion depthRectal cancerT3 substaging

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.