ArticleMuscle & nerve2022
Motor unit integrity in multifocal motor neuropathy: A systematic evaluation with CMAP scans.
Article in Muscle & nerve, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 7 citations in OpenAlex.
- Intravenous immunoglobulin frequency in multifocal motor neuropathy: a retrospective study of nerve conduction outcomes.BMC neurology · 2026Article
- Quantifying motor unit loss prior to functional impairment in muscles affected by amyotrophic lateral sclerosis.Clinical neurophysiology practice · 2026Article
- Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72.Annals of clinical and translational neurology · 2025Article
- Review
- Multifocal Motor Neuropathy: A Narrative Review.Muscle & nerve · 2025Review
- [Multifocal motor neuropathy. Report of three cases at a reference hospital in Mexico].Revista medica del Instituto Mexicano del Seguro Social · 2024Article
- Effect of surface electrode recording area on compound muscle action potential scan processing for motor unit number estimation.Frontiers in neuroscience · 2024Article
- Motor unit integrity in multifocal motor neuropathy: A systematic evaluation with CMAP scans.Muscle & nerve · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
INTRODUCTION/
aimsProgressive axonal loss in multifocal motor neuropathy (MMN) is often assessed with nerve conduction studies (NCS), by recording maximum compound muscle action potentials (CMAPs). However, reinnervation maintains the CMAP amplitude until a significant portion of the motor unit (MU) pool is lost. Therefore, we performed more informative CMAP scans to study MU characteristics in a large cohort of patients with MMN.
methodsWe derived the maximum CMAP amplitude (CMAP
resultsForty MMN patients and 24 healthy controls were included in the study. CMAP DISCUSSION: We found that MU loss is common in MMN and accompanied by enlarged MUs. Presence of anti-GM1 antibodies was associated with increased relative range of MU thresholds and reduction in largest MU amplitude. Our findings indicate that CMAP scans complement routine NCS, and may have potential for practical monitoring of treatment efficacy and disease progression.
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