Evidence map›Paper›PMID 34854455›Full record

ArticleNanoscale2021

The nanotopography of SiO

Robert Mills-Goodlet, Litty Johnson, Isabel J Hoppe, Christof Regl, Mark Geppert, Milena Schenck, Sara Huber, Michael Hauser, Fátima Ferreira, Nicola Hüsing and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Nanoscale, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Robert Mills-GoodletDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.ORCID http://orcid.org/0000-0002-7581-6771
Litty JohnsonDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.ORCID http://orcid.org/0000-0003-1462-4167
Isabel J HoppeDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.
Christof ReglDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.
Mark GeppertDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.ORCID http://orcid.org/0000-0001-6684-2508
Milena SchenckDept. Chemistry and Physics of Materials, Paris Lodron University of Salzburg, Austria.
Sara HuberDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.
Michael HauserDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.
Fátima FerreiraDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.
Nicola HüsingDept. Chemistry and Physics of Materials, Paris Lodron University of Salzburg, Austria.
Christian G HuberDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.
Hans BrandstetterDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.ORCID http://orcid.org/0000-0002-6089-3045
Albert DuschlDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.ORCID http://orcid.org/0000-0002-7034-9860
Martin HimlyDept. Biosciences, Paris Lodron University of Salzburg, Austria. martin.himly@plus.ac.at.ORCID http://orcid.org/0000-0001-5416-085X
University of Salzburg · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A detailed description of the changes that occur during the formation of protein corona represents a fundamental question in nanoscience, given that it not only impacts the behaviour of nanoparticles but also affects the bound proteins. Relevant questions include whether proteins selectively bind particles, whether a specific orientation is preferred for binding, and whether particle binding leads to a modulation of their 3D fold. For allergens, it is important to answer these questions given that all these effects can modify the allergenic response of atopic individuals. These potential impacts on the bound allergen are closely related to the specific properties of the involved nanoparticles. One important property influencing the formation of protein corona is the nanotopography of the particles. Herein, we studied the effect of nanoparticle porosity on allergen binding using mesoporous and non-porous SiO

Indexed as

AllergensSilicon DioxideAntigens, PlantHumansImmunoglobulin EPollenAllergensAntigens, PlantImmunoglobulin ESilicon Dioxide

Identifiers

PMID34854455
PMCPMC8675021
OpenAlexW3217006220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.