Evidence map›Paper›PMID 34854319›Full record

ArticleJournal of the American Heart Association2021

Real-Time Arrhythmia Detection Using Hybrid Convolutional Neural Networks.

Sandeep Chandra Bollepalli, Rahul K Sevakula, Wan-Tai M Au-Yeung, Mohamad B Kassab, Faisal M Merchant, George Bazoukis, Richard Boyer, Eric M Isselbacher, Antonis A Armoundas

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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  13. Current and Future Use of Artificial Intelligence in Electrocardiography.Journal of cardiovascular development and disease · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Sandeep Chandra BollepalliCardiovascular Research Center Massachusetts General Hospital Boston MA.ORCID 0000-0002-9971-9335
Rahul K SevakulaCardiovascular Research Center Massachusetts General Hospital Boston MA.ORCID 0000-0002-6234-367X
Wan-Tai M Au-YeungCardiovascular Research Center Massachusetts General Hospital Boston MA.
Mohamad B KassabCardiovascular Research Center Massachusetts General Hospital Boston MA.
Faisal M MerchantCardiology Division Emory University School of Medicine Atlanta GA.ORCID 0000-0003-0679-860X
George BazoukisSecond Department of Cardiology Evangelismos General Hospital of Athens Athens Greece.
Richard BoyerAnesthesia Department Massachusetts General Hospital Boston MA.
Eric M IsselbacherHealthcare Transformation Lab Massachusetts General Hospital Boston MA.
Antonis A ArmoundasCardiovascular Research Center Massachusetts General Hospital Boston MA.ORCID 0000-0001-5006-1547
Massachusetts General Hospital · USEmory University · USEvangelismos Hospital · GR

Funding

Harvard Clinical and Translational Science Center (UL1)UL1TR000170 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2012 to 2013
$31.4M
Prevention and Treatment of Ventricular TachyarrhythmiasR01HL135335 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ARMOUNDAS, ANTONIS A · 2017 to 2020
$2.1M
A Medical-Grade Smart-Phone Based Monitoring System (Supplement)R21EB026164 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI ARMOUNDAS, ANTONIS A · 2018 to 2020
$668k
Utility of Vagal Stimulation to Prevent the Onset of Ventricular ArrhythmiasR21HL137870 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ARMOUNDAS, ANTONIS A · 2017 to 2018
$468k
NCATS NIH HHS UL1 TR000170NHLBI NIH HHS R01 HL135335NHLBI NIH HHS R21 HL137870NIBIB NIH HHS R21 EB026164
6 · The paper itself

Abstract

Background Accurate detection of arrhythmic events in the intensive care units (ICU) is of paramount significance in providing timely care. However, traditional ICU monitors generate a high rate of false alarms causing alarm fatigue. In this work, we develop an algorithm to improve life threatening arrhythmia detection in the ICUs using a deep learning approach. Methods and Results This study involves a total of 953 independent life-threatening arrhythmia alarms generated from the ICU bedside monitors of 410 patients. Specifically, we used the ECG (4 channels), arterial blood pressure, and photoplethysmograph signals to accurately detect the onset and offset of various arrhythmias, without prior knowledge of the alarm type. We used a hybrid convolutional neural network based classifier that fuses traditional handcrafted features with features automatically learned using convolutional neural networks. Further, the proposed architecture remains flexible to be adapted to various arrhythmic conditions as well as multiple physiological signals. Our hybrid- convolutional neural network approach achieved superior performance compared with methods which only used convolutional neural network. We evaluated our algorithm using 5-fold cross-validation for 5 times and obtained an accuracy of 87.5%±0.5%, and a score of 81%±0.9%. Independent evaluation of our algorithm on the publicly available PhysioNet 2015 Challenge database resulted in overall classification accuracy and score of 93.9% and 84.3%, respectively, indicating its efficacy and generalizability. Conclusions Our method accurately detects multiple arrhythmic conditions. Suitable translation of our algorithm may significantly improve the quality of care in ICUs by reducing the burden of false alarms.

Indexed as

AlgorithmsArrhythmias, CardiacNeural Networks, ComputerHumansIntensive Care UnitsReproducibility of Resultsconvolutional neural networksfalse alarmsintensive care unit monitorsmachine learningmulti‐class classification

Identifiers

PMID34854319
PMCPMC9075394
OpenAlexW3217455057

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.