Evidence map›Paper›PMID 34854278›Full record

ArticleHaematologica2022

Biallelic CXCR2 loss-of-function mutations define a distinct congenital neutropenia entity.

Viviana Marin-Esteban, Jenny Youn, Blandine Beaupain, Agnieszka Jaracz-Ros, Vincent Barlogis, Odile Fenneteau, Thierry Leblanc, Florence Bellanger, Philippe Pellet, Julien Buratti and 4 more

Abstract read
In one paragraph

Article in Haematologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Case Report: NovelFrontiers in immunology · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Viviana Marin-EstebanUniversité Paris-Saclay, Inserm UMR996, Inflammation, Microbiome and Immunosurveillance. viviana.marin-esteban@universite-paris-saclay.fr.
Jenny YounSorbonne Université, Service d'Hémato-oncologie Pédiatrique, Assistance Publique-Hopitaux de Paris (AP-HP), Hôpital Trousseau.
Blandine BeaupainRegistre Français des Neutropénies Congénitales, Hôpital Trousseau, Paris; Centre de Référence des Neutropénies Chroniques, AP-HP, Hôpital Trousseau.
Agnieszka Jaracz-RosUniversité Paris-Saclay, Inserm UMR996, Inflammation, Microbiome and Immunosurveillance.
Vincent BarlogisCHU Marseille, Hôpital La Timone, Service d'Hémato-oncologie Pédiatrique, Assistance Publique-Hôpitaux de Marseille.
Odile FenneteauAP-HP, Laboratoire d'Hématologie, Hôpital Robert-Debré.
Thierry LeblancAP-HP, Hôpital Robert-Debré, Service d'Hématologie Pédiatrique.
Florence BellangerSorbonne Université, Département de Génétique Médicale, AP-HP, Hôpital Pitié-Salpêtrière.
Philippe PelletSorbonne Université, Département de Génétique Médicale, AP-HP, Hôpital Pitié-Salpêtrière.
Julien BurattiSorbonne Université, Département de Génétique Médicale, AP-HP, Hôpital Pitié-Salpêtrière.
Hélène LapillonneSorbonne Université, CRSA-Unité INSERM, AP-HP, Hôpital Trousseau, 75012 Paris.
Françoise BachelerieUniversité Paris-Saclay, Inserm UMR996, Inflammation, Microbiome and Immunosurveillance.
Jean DonadieuSorbonne Université, Service d'Hémato-oncologie Pédiatrique, Assistance Publique-Hopitaux de Paris (AP-HP), Hôpital Trousseau, Paris; Registre Français des Neutropénies Congénitales, Hôpital Trousseau, Paris; Centre de Référence des Neutropénies Chroniques, AP-HP, Hôpital Trousseau.
Christine Bellanné-ChantelotCentre de Référence des Neutropénies Chroniques, AP-HP, Hôpital Trousseau, Paris; Sorbonne Université, Département de Génétique Médicale, AP-HP, Hôpital Pitié-Salpêtrière, Paris; Inserm U1287, Villejuif. christine.bellanne-chantelot@aphp.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Congenital Bone Marrow Failure SyndromesNeutropeniaHumansLoss of Function MutationReceptors, Interleukin-8BCXCR2 protein, humanReceptors, Interleukin-8B

Identifiers

PMID34854278
PMCPMC8883555

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.