Evidence map›Paper›PMID 34854267›Full record

ArticleJournal of veterinary science2021

An outbreak of neonatal enteritis in buffalo calves associated with astrovirus.

Paolo Capozza, Vito Martella, Gianvito Lanave, Cristiana Catella, Georgia Diakoudi, Farzad Beikpour, Michele Camero, Barbara Di Martino, Giovanna Fusco, Anna Balestrieri and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Porcine astrovirus: a review.Archives of virology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Paolo CapozzaDepartment of Veterinary Medicine, University of Bari, Valenzano 70010, Italy.ORCID https://orcid.org/0000-0001-5563-1131
Vito MartellaDepartment of Veterinary Medicine, University of Bari, Valenzano 70010, Italy.ORCID https://orcid.org/0000-0002-5740-6947
Gianvito LanaveDepartment of Veterinary Medicine, University of Bari, Valenzano 70010, Italy. gianvito.lanave@uniba.it.ORCID https://orcid.org/0000-0003-4614-677X
Cristiana CatellaDepartment of Veterinary Medicine, University of Bari, Valenzano 70010, Italy.ORCID https://orcid.org/0000-0002-9594-5255
Georgia DiakoudiDepartment of Veterinary Medicine, University of Bari, Valenzano 70010, Italy.ORCID https://orcid.org/0000-0002-7305-5630
Farzad BeikpourDepartment of Veterinary Medicine, University of Bari, Valenzano 70010, Italy.ORCID https://orcid.org/0000-0001-9661-3917
Michele CameroDepartment of Veterinary Medicine, University of Bari, Valenzano 70010, Italy.ORCID https://orcid.org/0000-0003-0026-8325
Barbara Di MartinoFaculty of Veterinary Medicine, University of Teramo, Teramo 64100, Italy.ORCID https://orcid.org/0000-0001-6192-7166
Giovanna FuscoIstituto Zooprofilattico Sperimentale del Mezzogiorno, Portici 80055, Italy.ORCID https://orcid.org/0000-0003-3139-7672
Anna BalestrieriIstituto Zooprofilattico Sperimentale del Mezzogiorno, Portici 80055, Italy.ORCID https://orcid.org/0000-0001-6818-5628
Giuseppe CampanileDepartment of Veterinary Medicine and Animal Production, University of Naples, Naples 80137, Italy.ORCID https://orcid.org/0000-0002-3242-7274
Krisztian BanyaiInstitute for Veterinary Medical Research, Centre for Agricultural Research, Budapest 1143, Hungary.ORCID https://orcid.org/0000-0002-6270-1772
Canio BuonavogliaDepartment of Veterinary Medicine, University of Bari, Valenzano 70010, Italy.ORCID https://orcid.org/0000-0002-6149-0678
University of Bari Aldo Moro · ITIstituto Zooprofilattico Sperimentale del Mezzogiorno · ITHUN-REN Veterinary Medical Research Institute · HUUniversity of Naples Federico II · ITUniversity of Teramo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEnteritis of an infectious origin is a major cause of productivity and economic losses to cattle producers worldwide. Several pathogens are believed to cause or contribute to the development of calf diarrhea. Astroviruses (AstVs) are neglected enteric pathogens in ruminants, but they have recently gained attention because of their possible association with encephalitis in humans and various animal species, including cattle.

objectivesThis paper describes a large outbreak of neonatal diarrhea in buffalo calves (

methodsFollowing an enteritis outbreak characterized by high morbidity (100%) and mortality (46.2%) in a herd of Mediterranean buffaloes (

resultsThe samples tested negative for common enteric viral agents, including Rotavirus A, coronavirus, calicivirus, pestivirus, kobuvirus, and torovirus, while they tested positive for AstV. Overall, 62.5% (10/16) of the samples were positive in a single round reverse transcription polymerase chain reaction (PCR) assay for AstV, and 100% (16/16) were positive when nested PCR was performed. The strains identified in the outbreak showed a clonal origin and shared the closest genetic relationship with bovine AstVs (up to 85% amino acid identity in the capsid).

conclusionsThis report indicates that AstVs should be included in a differential diagnosis of infectious diarrhea in buffalo calves.

Indexed as

AnimalsAnimals, NewbornAstroviridaeAstroviridae InfectionsBuffaloesCapsid ProteinsDisease OutbreaksEnteritisGene Expression Regulation, EnzymologicGene Expression Regulation, ViralItalyPhylogenyRNA-Dependent RNA PolymeraseCapsid ProteinsRNA-Dependent RNA PolymeraseastroviridaeBuffaloenteritisinfection

Identifiers

PMID34854267
PMCPMC8636656
OpenAlexW3206600693

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.