ArticleAddiction (Abingdon, England)2022
Health impacts of a scale-up of supervised injection services in a Canadian setting: an interrupted time series analysis.
Article in Addiction (Abingdon, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.
- Harms associated with injecting in public spaces: a global systematic review and meta-analysis.The International journal on drug policy · 2025Pooled it
- Vending machines for reducing harm associated with substance use and use disorders, and co-occurring conditions: a systematic review.Harm reduction journal · 2025Pooled it
- Exploring the early impacts of drug decriminalization on harm reduction and opioid agonist treatment service operations and delivery in British Columbia: insights from key informant interviews.BMC public health · 2025Article
- A qualitative study exploring motives for the transition from injecting to smoking drugs in Vancouver, British Columbia.The International journal on drug policy · 2025Article
- Study assessing the effectiveness of overdose prevention centers through research (SAFER): an overview of the study protocol.Harm reduction journal · 2025Article
- Moral foundations underpinning attitudes toward supervised consumption services across Canada's prairie provinces.Harm reduction journal · 2025Article
- Four decades of overdose prevention centres: lessons for the future from a realist review.Harm reduction journal · 2025Review
- Scaling up hepatitis C testing and linkage-to-care among people who use drugs: lessons learned from a pilot project implemented at a supervised consumption site.BMC health services research · 2025Article
- Perspectives of key interest groups regarding supervised Consumption sites (SCS) and novel virtual harm reduction services / overdose response hotlines and applications: a qualitative Canadian study.Harm reduction journal · 2024Article
- A qualitative study on perceptions and experiences of overdose among people who smoke drugs in Vancouver, British Columbia.Drug and alcohol dependence · 2024Article
- Characterizing Use of Supervised Consumption Services among Street-involved Youth and Young Adults in the Context of an Overdose Crisis.Journal of urban health : bulletin of the New York Academy of Medicine · 2024Article
- Negative changes in illicit drug supply during COVID-19: Associations with use of overdose prevention and health services among women sex workers who use drugs (2020-2021).The International journal on drug policy · 2023Article
- "Safer Drug Supply" Measures in Canada to Reduce the Drug Overdose Fatality Toll: Clarifying Concepts, Practices and Evidence Within a Public Health Intervention Framework.Journal of studies on alcohol and drugs · 2023Article
- "We just don't have the space for it": Geographies of survival and spatial triage in overdose prevention sites.Health & place · 2023Article
- Community partner perspectives on the implementation of a novel safer supply program in Canada: a qualitative study of the MySafe Project.Harm reduction journal · 2023Article
- Moving towards a continuum of safer supply options for people who use drugs: A qualitative study exploring national perspectives on safer supply among professional stakeholders in Canada.Substance abuse treatment, prevention, and policy · 2022Article
- Observational
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
BACKGROUND AND
aimsIn response to a dramatic rise in overdose deaths due to injection drug use, there was a rapid scale-up of low-threshold supervised injection services (SIS), termed 'overdose prevention sites' (OPS), in Vancouver, Canada in December 2016. We measured the potential impact of this intervention on SIS use and related health outcomes among people who inject drugs (PWID).
designSegmented regression analyses of interrupted time series data from two community-recruited prospective cohorts of PWID from January 2015 to November 2018 were used to measure the impact of the OPS scale-up on changes in SIS use, public injection, syringe sharing and addiction treatment participation, controlling for pre-existing secular trends.
settingVancouver, Canada.
participantsOf 745 PWID, 292 (39.7%) were women, 441 (59.6%) self-reported white ancestry and the median age was 47 years (interquartile range = 38, 53) at baseline. MEASUREMENTS: Immediate (i.e. step level) and gradual (i.e. slope) changes in the monthly proportion of participants who self-reported past 6-month SIS use, public injection, syringe sharing and participation in any form of addiction treatment.
findingsPost OPS expansion, the monthly prevalence of SIS use immediately increased by an estimated 6.4% [95% confidence interval (CI) = 1.7, 11.2] and subsequently further increased by an estimated 0.7% (95% CI = 0.3, 1.1) per month. The monthly prevalence of addiction treatment participation immediately increased by an estimated 4.5% (95% CI = 0.5, 8.5) following the OPS expansion, while public injection and syringe sharing were estimated to immediately decrease by 5.5% (95% CI = 0.9, 10.0) and 2.5% (95% CI = 0.5, 4.6), respectively. Findings were inconclusive as to whether or not an association was present between the intervention and subsequent gradual changes in public injection, syringe sharing and addiction treatment participation.
conclusionsScaling-up overdose prevention sites in Vancouver, Canada in December 2016 was associated with immediate and continued gradual increases in supervised injection service engagement and immediate increases in related health benefits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.