SynthesisSports medicine (Auckland, N.Z.)2022
Effect of an Anterior Cruciate Ligament Rupture on Knee Proprioception Within 2 Years After Conservative and Operative Treatment: A Systematic Review with Meta-Analysis.
Synthesis in Sports medicine (Auckland, N.Z.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Return-to-Sport Outcomes and Psychological Readiness to Return to Sport After Revision Compared to the Primary Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-Analysis.Sports medicine - open · 2026Pooled it
- Pooled it
- Meta-analysis of the value of dual-energy computed tomography in the diagnosis of anterior cruciate ligament injuries of the knee.BMC musculoskeletal disorders · 2024Pooled it
- Acute anterior cruciate ligament rupture: can repair become an alternative to reconstruction: a meta-analysis of randomized controlled trials and cohort studies.Journal of orthopaedic surgery and research · 2024Pooled it
- Preserving Patient-Specific Knee Motion: A Randomized Clinical Trial of Unicompartmental and Total Knee Arthroplasty.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Trial
- Knee angle reproduction tests: influences of body orientation, movement direction and limb dominance.International journal of sports medicine · 2025Trial
- Comparison of proprioception recovery following anterior cruciate ligament reconstruction using an artificial graft versus an autograft.BMC musculoskeletal disorders · 2022Trial
- Disrupted sensorimotor control after ACL injury: from mechanoreceptor degeneration to neuroplasticity-oriented rehabilitation.Annals of medicine · 2026Review
- "It's a black box": Physiotherapists' perspectives on sensorimotor control and the use of technology in this context to improve rehabilitation following ACL injury.BMC musculoskeletal disorders · 2026Article
- ACL injuries in elite alpine skiing reliably allow athletes to return to competition and perform at or above their pre-injury level.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Knee valgus proprioception, muscle activity, patient-reported outcomes and dynamic balance control after anterior cruciate ligament reconstruction: a cross-sectional case-control study.Knee surgery & related research · 2026Article
- Effects of controlling anterior tibial translation preserve sensory-motor function and mechanoreceptor morphology following anterior cruciate ligament injury in rats.Scientific reports · 2026Article
- Durable mid-term survivorship after proximal ACL repair with suture augmentation in a middle-aged cohort: A risk factor analysis.Journal of experimental orthopaedics · 2026Article
- Validity and Reliability of a Laser Pointer Device to Assess Knee Proprioception in Healthy and Active Individuals.Physiotherapy research international : the journal for researchers and clinicians in physical therapy · 2026Article
- Anterior cruciate ligament reconstruction is associated with increased corticospinal excitability and rate of force development.BMC sports science, medicine & rehabilitation · 2026Article
- Evolution of pre- and post-operative balance characteristics in patients undergoing anterior cruciate ligament reconstruction: implications for rehabilitation.Frontiers in bioengineering and biotechnology · 2026Article
- Postural control and knee joint importance during quiet standing in individuals with anterior cruciate ligament reconstruction.PloS one · 2026Article
- Early improvement in shoulder external rotation proprioception after arthroscopic rotator cuff repair: an AMEDA-based quantitative assessment.Frontiers in bioengineering and biotechnology · 2026Article
- Reliability of a Lower-Extremity Shear Force Control Task in Young, Uninjured Adults.Journal of applied biomechanics · 2025Article
- Why Should Return to Sport Be Delayed by up to Two Years After ACL Reconstruction? A Narrative Review of the Biological, Surgical and Rehabilitation Evidence.Journal of clinical medicine · 2025Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe anterior cruciate ligament (ACL) plays a major role in knee proprioception and is thus responsible for maintaining knee joint stability and functionality. The available evidence suggests that ACL reconstruction diminishes somatosensory feedback and proprioceptive functioning, which are vital for adequate joint positioning and movement control.
objectiveThe aim of this systematic review and meta-analysis was to investigate the effect of an ACL rupture on knee proprioception after arthroscopic ACL repair surgery or conservative treatment.
methodsA systematic review with meta-analysis was conducted according to the Preferred Reporting Guidelines for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The literature search was performed in the following databases from inception to 10th October 2020: PubMed, Web of Science, SPORTDiscus, Cochrane Library and Scopus. Randomized and non-randomized studies that evaluated proprioception using the joint position sense (JPS) and threshold to detection of passive motion (TTDPM) techniques at 15°-30° knee flexion with an external healthy control group in a time period between 6 and 24 months post injury or operation were included in the analysis.
resultsIn total, 4857 studies were identified, from which 11 were included in the final quantitative analysis. The results demonstrated that proprioception after arthroscopic ACL repair surgery was significantly lower than in the healthy control group (JPS: standardized mean difference [SMD] 0.57, 95% confidence interval [CI] 0.27-0.87, p < 0.01, n = 6 studies; TTDPM: SMD 0.77, 95% CI 0.20-1.34, p < 0.01, n = 4 studies). There were no significant differences in proprioception between the conservative treatment group and the healthy control group (JPS: SMD 0.57, 95% CI - 0.69 to 1.84, p = 0.37, n = 4 studies; TTDPM: SMD 0.82, 95% CI - 0.02 to 1.65, p = 0.05, n = 2 studies), although measures for TTDPM were close to statistical significance.
conclusionThe findings of the present systematic review and meta-analysis revealed that knee proprioception is persistently compromised 6-24 months following surgical treatment of ACL tears compared with healthy controls. The reduced kinesthetic awareness after ACL surgery is of high relevance for optimizing individual treatment plans in these patients. As the current literature is still scarce about the exact underlying mechanisms, further research is needed.
trial registrationThe present systematic review was registered in PROSPERO (CRD42021198617).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.