ArticleWorld journal of pediatrics : WJP2022
Surgical management in pediatric neuroblastoma diagnosis and treatment: a 20-year, single-center experience.
Article in World journal of pediatrics : WJP, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 6 citations in OpenAlex.
- Multimodal magnetic resonance imaging in neuroblastoma chemotherapy: a narrative review.World journal of surgical oncology · 2026Review
- Association of image-defined risk factors with clinical features in thoracic neuroblastoma and the development of a prognostic prediction model.Frontiers in pediatrics · 2026Article
- An Unusual Cause of Persistent Wheeze in Infancy: Intrathoracic Neuroblastoma of the Lower Thoracic Sympathetic Chain.Case reports in pulmonology · 2026Article
- International Society of Paediatric Surgical Oncology (IPSO) Minimally Invasive Surgery (MIS) Guidelines.Ecancermedicalscience · 2026Article
- DNAJC12 downregulation induces neuroblastoma progression via increased histone H4K5 lactylation.Journal of molecular cell biology · 2025Article
- Fatty acid metabolism-related risk signature revealing the immune landscape of neuroblastoma and predicting overall survival in pediatric neuroblastoma patients.Discover oncology · 2025Article
- Minimally invasive surgery in neurogenic tumours.Ecancermedicalscience · 2025Review
- Article
- Perioperative complication incidence and risk factors for retroperitoneal neuroblastoma in children: analysis of 571 patients.World journal of pediatrics : WJP · 2024Article
- A novel cuproptosis-related gene signature predicting overall survival in pediatric neuroblastoma patients.Frontiers in pediatrics · 2022Article
- Surgical Treatment of Adrenal Neuroblastoma in Children - A Narrative Review.International braz j urol : official journal of the Brazilian Society of UrologyReview
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe currently utilized International Neuroblastoma Risk Group (INRG) staging system developed in 2009 uses image-defined risk factors as a measure of surgical risk, separating resectable neuroblastoma from those best preceded by chemotherapy. The previous International Neuroblastoma Staging System was based primarily on surgical findings. We hypothesized there would be a change to the role of the surgeon in neuroblastoma treatment in the more recent decade.
methodsThis is a single center 20-year retrospective analysis of 104 patients with International Classification of Diseases-9 and -10 codes for neuroblastoma. Patient demographics, tumor site, cancer treatment modality, survival, biopsy technique, surgical intervention, and pathology staging were collected. Data was analyzed by analysis of variance (ANOVA) and Student's t test.
resultsThere was a decrease in open surgeries for extra-adrenal neuroblastomas in the later decade (77%, 31%, P = 0.01). There was a narrowing of the time interval to surgery in the later cohort, likely as a result of uniformity in surgical timing on treatment protocols relying on INRG staging.
conclusionsOur findings mirror changes in practice patterns globally. We found an increase in minimally invasive approaches but did not find a difference in the role of the surgeon under the INRG staging system.
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