Evidence map›Paper›PMID 34853921›Full record

ArticleAnnals of biomedical engineering2021

Prediction of Ventricular Mechanics After Pulmonary Valve Replacement in Tetralogy of Fallot by Biomechanical Modeling: A Step Towards Precision Healthcare.

Maria Gusseva, Tarique Hussain, Camille Hancock Friesen, Gerald Greil, Dominique Chapelle, Radomír Chabiniok

Abstract read
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In one paragraph

Article in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. A modelling study of right ventricular growth with valvular regurgitation.Biomechanics and modeling in mechanobiology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Clinical Applications of Pressure-Volume Assessment in Congenital Heart Disease.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Maria GussevaInria, Palaiseau, France.
Tarique HussainDivision of Pediatric Cardiology, Department of Pediatrics, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.
Camille Hancock FriesenDivision of Pediatric Cardiothoracic Surgery, Department of Surgery, University of Nebraska, Medical Center College of Medicine, Omaha, NE, USA.
Gerald GreilDivision of Pediatric Cardiology, Department of Pediatrics, UT Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390, USA.
Dominique ChapelleInria, Palaiseau, France.
Radomír ChabiniokInria, Palaiseau, France. radomir.chabiniok@UTSouthwestern.edu.ORCID http://orcid.org/0000-0002-7527-2751
Centre National de la Recherche Scientifique · FRSouthwestern Medical CenterUniversity of Nebraska Medical Center · US

Funding

Inria Inria-UTSW Associated Team TOFMODMinisterstvo Zdravotnictví Ceské Republiky NV19-08-00071Pogue Family Pogue Family Distinguished Chair
6 · The paper itself

Abstract

Clinical indicators of heart function are often limited in their ability to accurately evaluate the current mechanical state of the myocardium. Biomechanical modeling has been shown to be a promising tool in addition to clinical indicators. By providing a patient-specific measure of myocardial active stress (contractility), biomechanical modeling can enhance the precision of the description of patient's pathophysiology at any given point in time. In this work we aim to explore the ability of biomechanical modeling to predict the response of ventricular mechanics to the progressively decreasing afterload in repaired tetralogy of Fallot (rTOF) patients undergoing pulmonary valve replacement (PVR) for significant residual right ventricular outflow tract obstruction (RVOTO). We used 19 patient-specific models of patients with rTOF prior to pulmonary valve replacement (PVR), denoted as PSM

Indexed as

Precision MedicineBiomechanical PhenomenaHeart Valve Prosthesis ImplantationHumansModels, CardiovascularPostoperative ComplicationsPredictive Value of TestsPulmonary ValveTetralogy of FallotVentricular Outflow ObstructionVentricular RemodelingBiomechanical modelingMyocardial contractilityValve replacementValvular heart diseaseVentricular overload

Identifiers

PMID34853921
OpenAlexW3217677930

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.