Evidence map›Paper›PMID 34853814›Full record

ArticleMolecular therapy oncolytics2021

Selective sodium iodide symporter (

Rebekka Spellerberg, Teoman Benli-Hoppe, Carolin Kitzberger, Simone Berger, Kathrin A Schmohl, Nathalie Schwenk, Hsi-Yu Yen, Christian Zach, Franz Schilling, Wolfgang A Weber and 5 more

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy oncolytics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Disulfiram metabolite Cu(DDC)EBioMedicine · 2026
    Article
  2. Recent developments in translational imaging of in vivo gene therapy outcomes.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 2 countries.

Rebekka SpellerbergDepartment of Internal Medicine IV, University Hospital, LMU Munich, 81377 Munich, Germany.
Teoman Benli-HoppePharmaceutical Biotechnology, Department of Pharmacy, LMU Munich, 81377 Munich, Germany.
Carolin KitzbergerDepartment of Internal Medicine IV, University Hospital, LMU Munich, 81377 Munich, Germany.
Simone BergerPharmaceutical Biotechnology, Department of Pharmacy, LMU Munich, 81377 Munich, Germany.
Kathrin A SchmohlDepartment of Internal Medicine IV, University Hospital, LMU Munich, 81377 Munich, Germany.
Nathalie SchwenkDepartment of Internal Medicine IV, University Hospital, LMU Munich, 81377 Munich, Germany.
Hsi-Yu YenInstitute of Pathology, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Christian ZachDepartment of Nuclear Medicine, University Hospital, LMU Munich, 81377 Munich, Germany.
Franz SchillingDepartment of Nuclear Medicine, School of Medicine, Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany.
Wolfgang A WeberDepartment of Nuclear Medicine, School of Medicine, Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany.
Roland E KälinNeurosurgical Research, Department of Neurosurgery, University Hospital, LMU Munich, 81377 Munich, Germany.
Rainer GlassNeurosurgical Research, Department of Neurosurgery, University Hospital, LMU Munich, 81377 Munich, Germany.
Peter J NelsonDepartment of Internal Medicine IV, University Hospital, LMU Munich, 81377 Munich, Germany.
Ernst WagnerPharmaceutical Biotechnology, Department of Pharmacy, LMU Munich, 81377 Munich, Germany.
Christine SpitzwegDepartment of Internal Medicine IV, University Hospital, LMU Munich, 81377 Munich, Germany.
LMU Klinikum · DELudwig-Maximilians-Universität München · DETUM Klinikum · DEGerman Cancer Research Center · DETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipo-oligomers, post-functionalized with ligands to enhance targeting, represent promising new vehicles for the tumor-specific delivery of therapeutic genes such as the sodium iodide symporter (

Indexed as

DNA nanoparticleEGFR-targetingGBMgene therapyglioblastomaNISpolyplexesradioiodinesodium iodide symporter

Identifiers

PMID34853814
PMCPMC8604759
OpenAlexW3208053489

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.