Evidence map›Paper›PMID 34853796›Full record

ArticleMolecular therapy. Methods & clinical development2021

Characterization of a library of 20 HBV-specific MHC class II-restricted T cell receptors.

Sophia Schreiber, Melanie Honz, Weeda Mamozai, Peter Kurktschiev, Matthias Schiemann, Klaus Witter, Eugene Moore, Christina Zielinski, Alessandro Sette, Ulrike Protzer and 1 more

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy. Methods & clinical development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Sophia SchreiberInstitute of Virology, Helmholtz Zentrum München, 81675 Munich, Germany.
Melanie HonzInstitute of Virology, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Weeda MamozaiInstitute of Virology, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Peter KurktschievMedical Department II and Institute for Immunology, Hospital of the Ludwig-Maximilians-University (LMU) Munich, 81377 Munich, Germany.
Matthias SchiemannInstitute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Klaus WitterLaboratory for Immunogenetics and Molecular Diagnostics, Hospital of the Ludwig-Maximilians-University (LMU) Munich, 81377 Munich, Germany.
Eugene MooreCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Christina ZielinskiInstitute of Virology, School of Medicine, Technical University of Munich, 81675 Munich, Germany.
Alessandro SetteCenter for Infectious Disease and Vaccine Research, La Jolla Institute for Immunology (LJI), La Jolla, CA 92037, USA.
Ulrike ProtzerInstitute of Virology, Helmholtz Zentrum München, 81675 Munich, Germany.
Karin WisskirchenInstitute of Virology, Helmholtz Zentrum München, 81675 Munich, Germany.
Helmholtz Zentrum München · DEGerman Center for Infection Research · DELa Jolla Institute for Immunology · USLudwig-Maximilians-Universität München · DETechnical University of Munich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD4

Indexed as

adoptive T cell therapyCD4+ T cellschronic hepatitis BHBV clearancehepatitis B virus infectionhepatocellular carcinomaMHC class II-restricted T cell receptorsretroviral transductionT cell helpTCR expression

Identifiers

PMID34853796
PMCPMC8605085
OpenAlexW3208485471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.