Evidence map›Paper›PMID 34853787›Full record

ArticleBioMed research international2021

Long-Term Carbohydrate-Containing Late-Evening Snack Significantly Improves the Ratio of Branched Chain Amino Acids to Aromatic Amino Acids in Adults with Liver Cirrhosis due to Hepatitis B.

Wei Hou, Zheng Lv, Jing Yang, Jing Wu, Zhong-Ying Wang, Qing-Hua Meng

RetractedOpen access · hybridAbstract readRetracted Publication
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wei HouDepartment of Critical Care Medicine of Liver Disease, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
Zheng LvDepartment of Critical Care Medicine of Liver Disease, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
Jing YangDepartment of Critical Care Medicine of Liver Disease, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
Jing WuDepartment of Critical Care Medicine of Liver Disease, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
Zhong-Ying WangDepartment of Critical Care Medicine of Liver Disease, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.
Qing-Hua MengDepartment of Critical Care Medicine of Liver Disease, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China.ORCID https://orcid.org/0000-0003-0587-2855
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe liver is the primary organ for amino acid metabolism, and metabolic disorder of amino acids is common in liver disease. However, the characteristics of plasma amino acid profiles in patients with HBV-related cirrhosis and the impacts of late-evening snack (LES) on cirrhosis are unclear.

objectivesTo investigate the characteristics of plasma amino acid profiles in patients with HBV-related chronic hepatitis, cirrhosis, and the effects of late-evening snacks on plasma amino acid profiles.

methods86 patients with HBV-related cirrhosis and eighty patients with chronic hepatitis B were included in this study. The plasma amino acid profiles were measured by the amino acid analyzer. Patients were randomly divided into two groups, of which the liver cirrhosis group was to receive daily LES (

resultsCompared to healthy controls, the plasma concentration in the liver cirrhosis group of threonine, serine, glycine, glutamine, cysteine, tyrosine, phenylalanine, arginine, and methionine increased significantly (

conclusionsThe application of an LES carbohydrate module for six months in liver cirrhosis patients was associated with increased BCAA/AAA and decreased level of ammonia. Patients with Child-Pugh B and C grades were the most beneficial population.

Indexed as

AdultAmino Acids, AromaticAmino Acids, Branched-ChainAmmoniaCase-Control StudiesDietary CarbohydratesFemaleGlutamineHepatitis B, ChronicHumansLiver CirrhosisMaleMiddle AgedSnacksAmino Acids, AromaticAmino Acids, Branched-ChainAmmoniaDietary CarbohydratesGlutamine

Identifiers

PMID34853787
PMCPMC8629637
OpenAlexW3216141293

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.