Evidence map›Paper›PMID 34853726›Full record

ReviewMolecular therapy. Nucleic acids2021

The roles and mechanisms of the m6A reader protein YTHDF1 in tumor biology and human diseases.

Zuyao Chen, Xiaolin Zhong, Min Xia, Jing Zhong

Open access · goldAbstract readReview
In one paragraph

Review in Molecular therapy. Nucleic acids, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. mCell death and differentiation · 2026
    Article
  3. Article
  4. Review
  5. NBiomolecules · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. mActa pharmaceutica Sinica. B · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. The mMolecular biomedicine · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. N6-methyladenosine methylation: a novel key to unlocking mental disorders.The international journal of neuropsychopharmacology · 2025
    Review
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zuyao ChenHengyang Medical School, University of South China, 421001 Hengyang, Hunan, China.
Xiaolin ZhongHengyang Medical School, University of South China, 421001 Hengyang, Hunan, China.
Min XiaHengyang Medical School, University of South China, 421001 Hengyang, Hunan, China.
Jing ZhongHengyang Medical School, University of South China, 421001 Hengyang, Hunan, China.
University of South China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

YTHDF1 is the most versatile and powerful reader protein of

Indexed as

m6AmRNA stabilityN6-methyladenosineprotein translationtumor biologyYTHDF1

Identifiers

PMID34853726
PMCPMC8609105
OpenAlexW3212862531

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.