ReviewEvolution, medicine, and public health2021
Five reasons COVID-19 is less severe in younger age-groups.
Review in Evolution, medicine, and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Face First: The Role of Age and Sex in the Epidemiology of Facial Fractures.Dentistry journal · 2025Article
- Article
- Technical efficiency and its determinants in regulating adolescents' coronavirus infection across Asian countries.Scientific reports · 2023Article
- COVID-19 andEvolution, medicine, and public health · 2023Article
- Article
- Potential Application of SARS-CoV-2 Rapid Antigen Diagnostic Tests for the Detection of Infectious Individuals Attending Mass Gatherings - A Simulation Study.Frontiers in epidemiology · 2022Article
- Classification of COVID-19 and Influenza Patients Using Deep Learning.Contrast media & molecular imaging · 2022Article
- Evaluation of Three Multiplex Real-time Reverse Transcription PCR Assays for Simultaneous Detection of SARS-CoV-2, Influenza A/B, and Respiratory Syncytial Virus in Nasopharyngeal Swabs.Journal of Korean medical science · 2021Article
- One Year of the COVID-19 Pandemic in Galicia: A Global View of Age-Group Statistics during Three Waves.International journal of environmental research and public health · 2021Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The severity of COVID-19 is age-related, with the advantage going to younger age-groups. Five reasons are presented. The first two are well-known, are being actively researched by the broader medical community, and therefore are discussed only briefly here. The third, fourth and fifth reasons derive from evolutionary life history theory, and potentially fill gaps in current understanding of why and how young and old age-groups respond differently to infection with SARS-CoV-2. Age of onset of generalized somatic aging and the timing of its progression are identified as important causes of these disparities, as are specific antagonistic pleiotropic tradeoffs in immune system function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.