Evidence map›Paper›PMID 34853619›Full record

ArticleDisease markers2021

The Role of Fecal

Kaixi Liu, Xinran Yang, Mi Zeng, Yumeng Yuan, Jianhong Sun, Ping He, Jiayu Sun, Qingdong Xie, Xiaolan Chang, Suwei Zhang and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 48 citations in OpenAlex.

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  15. Potential and application ofFrontiers in microbiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Kaixi LiuDepartments of Clinical Laboratory, Shantou Central Hospital, Shantou, China.
Xinran YangDepartments of Clinical Laboratory, The First Affiliated Hospital of Shantou University Medical College, China.
Mi ZengMedical College of Shantou University, Shantou, China.
Yumeng YuanMedical College of Shantou University, Shantou, China.
Jianhong SunDepartments of Clinical Pathology, Shantou Central Hospital, Shantou, China.
Ping HeMedical College of Shantou University, Shantou, China.
Jiayu SunMedical College of Shantou University, Shantou, China.
Qingdong XieMedical College of Shantou University, Shantou, China.
Xiaolan ChangMedical College of Shantou University, Shantou, China.
Suwei ZhangDepartments of Clinical Laboratory, Shantou Central Hospital, Shantou, China.
Xiang ChenDepartments of Health Care Center, The First Affiliated Hospital of Shantou University Medical College, China.
Leshan CaiDepartments of Clinical Laboratory, The First Affiliated Hospital of Shantou University Medical College, China.
Yanxuan XieDepartments of Clinical Laboratory, The First Affiliated Hospital of Shantou University Medical College, China.
Xiaoyang JiaoMedical College of Shantou University, Shantou, China.ORCID https://orcid.org/0000-0002-7568-0595
Shantou University · CNShantou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate analysis of intestinal microbiota will facilitate establishment of an evaluating system for assessing colorectal cancer (CRC) risk and prognosis. This study evaluates the potential role of

methodsWe recruited 139 patients, including CRC (

resultsFecal

conclusionOur results suggested that combining bacterial markers with conventional tumor markers improves the diagnostic efficiency for noninvasive diagnosis of CRC.

Indexed as

Gastrointestinal MicrobiomeAgedBiomarkers, TumorCase-Control StudiesChinaColorectal NeoplasmsEarly Detection of CancerEscherichia coliFecesFemaleFollow-Up StudiesFusobacterium nucleatumHumansMaleMiddle AgedPrognosisBiomarkers, Tumor

Identifiers

PMID34853619
PMCPMC8629656
OpenAlexW3217113746

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.